It remains uncertain how tissue-specific stem cells could generate the mature cell types of another tissue. In one instance, where bone-marrow-derived stem cells repair damaged liver in mice, cell fusion is the answer.
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Medvinsky, A., Smith, A. Fusion brings down barriers. Nature 422, 823–825 (2003). https://doi.org/10.1038/422823a
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DOI: https://doi.org/10.1038/422823a
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