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Cost-free longevity in mice?

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Studies of worms have revealed hundreds of proteins that, when mutated, extend lifespan. Can this work tell us anything about mammalian ageing? A look at the effects of one such protein on lab mice suggests that it can.

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Figure 1: Genetic dissection of the hormonal determinants of mammalian lifespan.

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Authors and Affiliations

  1. The Buck Institute, 8001 Redwood Boulevard, Novato, 94949, California, USA

    Gordon J. Lithgow & Matthew S. Gill

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  1. Gordon J. Lithgow
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  2. Matthew S. Gill
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Correspondence to Gordon J. Lithgow or Matthew S. Gill.

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Lithgow, G., Gill, M. Cost-free longevity in mice?. Nature 421, 125–126 (2003). https://doi.org/10.1038/421125a

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