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Functional genomics

A time and place for every gene

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One benefit of studying mice is that most of their genes have counterparts in humans. Two groups have used this similarity to study when and where the genes found on human chromosome 21 are switched on.

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Figure 1: Analysing gene expression in the heart by in situ hybridization.

References

  1. The Chromosome 21 Mapping and Sequencing Consortium Nature 405, 311–319 (2000).

  2. Reymond, A. et al. Nature 420, 582–586 (2002).

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  3. The HSA21 expression map initiative Nature 420, 586–590 (2002).

  4. Ewing, R. M. et al. Genome Res. 9, 950–959 (1999).

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Authors and Affiliations

  1. Department of Physiology and the McKusick–Nathans Institute for Genetic Medicine, Johns Hopkins University School of Medicine, 725 North Wolfe Street, Baltimore, 21205-2105, Maryland, USA

    Roger H. Reeves

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  1. Roger H. Reeves
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Correspondence to Roger H. Reeves.

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Reeves, R. A time and place for every gene. Nature 420, 518–519 (2002). https://doi.org/10.1038/420518a

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