Skip to main content
SpringerLink
Log in

Cancer

New-age tumour suppressors

  • News & Views
  • Published:

From Nature

View current issue Submit your manuscript

The discovery of a gene that is inactivated in stomach cancers illustrates the value of mouse models for finding tumour-suppressor genes that are switched off by mechanisms other than mutation.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

References

  1. Cavenee, W. K. et al. Nature 305, 779–784 (1983).

    Article  ADS  CAS  PubMed  Google Scholar 

  2. Balmain, A. Nature Rev. Cancer 1, 77–82 (2001).

    Article  CAS  Google Scholar 

  3. Li, Q. L. et al. Cell 109, 113–124 (2002).

    Article  CAS  PubMed  Google Scholar 

  4. Jones, P. A. & Laird, P. W. Nature Genet. 21, 163–167 (1999).

    Article  CAS  PubMed  Google Scholar 

  5. Lerman, M. I. & Minna, J. D. Cancer Res. 60, 6116–6133 (2000).

    CAS  PubMed  Google Scholar 

  6. Dammann, R. et al. Nature Genet. 25, 315–319 (2000).

    Article  CAS  PubMed  Google Scholar 

  7. Philipp-Staheli, J., Payne, S. R. & Kemp, C. J. Exp. Cell Res. 264, 148–168 (2001).

    Article  CAS  PubMed  Google Scholar 

  8. Cohen, M. M. Am. J. Med. Genet. 104, 185–188 (2001).

    Article  PubMed  Google Scholar 

  9. Hanai, J. et al. J. Biol. Chem. 274, 31577–31582 (1999).

    Article  CAS  PubMed  Google Scholar 

  10. Derynck, R., Akhurst, R. & Balmain, A. Nature Genet. 29, 117–129 (2001).

    Article  CAS  PubMed  Google Scholar 

  11. Oft, M., Akhurst, R. J. & Balmain, A. Nature Cell Biol. (in the press).

  12. Osato, M. et al. Blood 93, 1817–1824 (1999).

    CAS  PubMed  Google Scholar 

  13. Blyth, K. et al. Oncogene 20, 295–302 (2001).

    Article  CAS  PubMed  Google Scholar 

  14. Stewart, M., MacKay, N., Cameron, E. R. & Neil, J. C. J. Virol. 76, 4364–4369 (2002).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  15. Brown, R. & Strathdee, G. Trends Mol. Med. 8, S43–S48 (2002).

    Article  CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. the UCSF Comprehensive Cancer Center, 2340 Sutter Street, San Francisco, 94115, California, USA

    Allan Balmain

Authors
  1. Allan Balmain
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Allan Balmain.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Balmain, A. New-age tumour suppressors. Nature 417, 235–237 (2002). https://doi.org/10.1038/417235a

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/417235a

  • Springer Nature Limited

This article is cited by

Search

Navigation