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Anandamide may mediate sleep induction

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Figure 1: Dose-dependent inhibition of [14C]anandamide hydrolysis by N18TG2 cell 10,000g particulate fractions.

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Authors and Affiliations

  1. Department of Natural Products, David Bloom Centre for Pharmacy, Faculty of Medicine, Hebrew University, Jerusalem, 91120, Israel

    Raphael Mechoulam, Ester Fride, Lumir Hanu & Tzviel Sheskin

  2. Istituto per la Chimica di Molecole di Interesse Biologico, Via Toiano 6, Arco Felice, 80072, Naples, Italy

    Tiziana Bisogno & Vincenzo Di Marzo

  3. Department of Neurobiology, Weizmann Institute of Science, Rehovot, 76100, Israel

    Michael Bayewitch & Zvi Vogel

Authors
  1. Raphael Mechoulam
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  2. Ester Fride
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  3. Lumir Hanu
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  4. Tzviel Sheskin
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  5. Tiziana Bisogno
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  6. Vincenzo Di Marzo
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  7. Michael Bayewitch
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  8. Zvi Vogel
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Mechoulam, R., Fride, E., Hanu, L. et al. Anandamide may mediate sleep induction. Nature 389, 25–26 (1997). https://doi.org/10.1038/37891

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