References
Renaud, F. & de Logeril, M. Lancet 339, 1523–1526 (1992).
Gibbs, C. S. et al. Nature 378, 413–416 (1995).
Esmon, C. T. Arterioscl. Thromb. 12, 135–145 (1992).
Hanson, S. R. et al. J. clin. Invest. 92, 2003–2012 (1993).
Gruber, A. et al. Circulation 84, 2454–2462 (1991).
Heeb, M. J. et al. J. biol. Chem. 266, 17606–17612 (1991).
Taylor, F. B. Jr et al. J. clin. Invest. 79, 918–925 (1987).
Grey, S. T. et al. J. Immun. 153, 3664–3672 (1994).
Wu, Q. et al. Proc. natn. Acad. Sci. U.S.A. 88, 6675–6679 (1991).
Tsiang, T. et al. J. biol. Chem. 270, 16854–16863 (1995).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Griffin, J. The thrombin paradox. Nature 378, 337–338 (1995). https://doi.org/10.1038/378337a0
Published:
Issue Date:
DOI: https://doi.org/10.1038/378337a0
- Springer Nature Limited
This article is cited by
-
Large-scale molecular dynamics simulation: Effect of polarization on thrombin-ligand binding energy
Scientific Reports (2016)
-
Counteracting clotting in sepsis
Nature Medicine (2008)
-
Thrombin: A paradigm for enzymes allosterically activated by monovalent cations
Rendiconti Lincei (2006)
-
Activated protein C blocks p53-mediated apoptosis in ischemic human brain endothelium and is neuroprotective
Nature Medicine (2003)
-
Not just an active site
Nature (2000)