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Controlling chaos in the brain

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Abstract

In a spontaneously bursting neuronal network in vitro, chaos can be demonstrated by the presence of unstable fixed-point behaviour. Chaos control techniques can increase the periodicity of such neuronal population bursting behaviour. Periodic pacing is also effective in entraining such systems, although in a qualitatively different fashion. Using a strategy of anticontrol such systems can be made less periodic. These techniques may be applicable to in vivo epileptic foci.

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Authors and Affiliations

  1. Department of Neurosurgery, Children's National Medical Center and The George Washington University School of Medicine, Washington DC, 20010, USA

    Steven J. Schiff, Kristin Jerger, Duc H. Duong & Taeun Chang

  2. Naval Surface Warfare Center, White Oak Laboratory, Silver Spring, Maryland, 20903, USA

    Mark L. Spano

  3. School of Physics, Georgia Institute of Technology, Atlanta, Georgia, 30332, USA

    William L. Ditto

Authors
  1. Steven J. Schiff
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  2. Kristin Jerger
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  3. Duc H. Duong
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  4. Taeun Chang
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  5. Mark L. Spano
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  6. William L. Ditto
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Schiff, S., Jerger, K., Duong, D. et al. Controlling chaos in the brain. Nature 370, 615–620 (1994). https://doi.org/10.1038/370615a0

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  • DOI: https://doi.org/10.1038/370615a0

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