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Alzheimer's disease

An inflammatory drug prospect

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There is no known cure for Alzheimer's disease. But new hope (for mice at least) comes from an in-depth investigation of a class of drugs used to treat inflammatory diseases.

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Figure 1: Alzheimer's and amyloid.
Figure 2: Strategies for reducing the levels of amyloid peptides in the body.

References

  1. McGeer, P. L., Schulzer, M. & McGeer, E. G. Neurology 47, 425–432 (1996).

    Article  CAS  Google Scholar 

  2. Breitner, J. C. Annu. Rev. Med. 47, 401–411 (1996).

    Article  CAS  Google Scholar 

  3. Weggen, S. et al. Nature 414, 212–216 (2001).

    Article  ADS  CAS  Google Scholar 

  4. Dominguez, D. I., De Strooper, B. & Annaert, W. Amyloid 8, 124–142 (2001).

    Article  CAS  Google Scholar 

  5. Selkoe, D. J. Nature 399, A23–A31 (1999).

  6. De Strooper, B. et al. Nature 398, 518–522 (1999).

    Article  ADS  Google Scholar 

  7. Scheuner, D. et al. Nature Med. 2, 864–870 (1996).

    Article  CAS  Google Scholar 

  8. Li, Y. M. et al. Nature 405, 689–694 (2000).

    Article  ADS  CAS  Google Scholar 

  9. Lim, G. P. et al. J. Neurosci. 20, 5709–5714 (2000).

    Article  CAS  Google Scholar 

  10. Jones, R. W. Lancet 358, 436–437 (2001).

    Article  CAS  Google Scholar 

  11. Van Gool, W. A. et al. Lancet 358, 455–460 (2001).

    Article  Google Scholar 

  12. Aisen, P. S. et al. Neurology 54, 588–593 (2000).

    Article  CAS  Google Scholar 

  13. Schenk, D. et al. Nature 400, 173–177 (1999).

    Article  ADS  CAS  Google Scholar 

  14. Fassbender, K. et al. Proc. Natl Acad. Sci. USA 98, 5856–5861 (2001).

    Article  ADS  CAS  Google Scholar 

  15. Cherny, R. A. et al. Neuron 30, 665–676 (2001).

    Article  CAS  Google Scholar 

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Correspondence to Bart De Strooper or Gerhard König.

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De Strooper, B., König, G. An inflammatory drug prospect. Nature 414, 159–160 (2001). https://doi.org/10.1038/35102656

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