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TACCing down the spindle poles

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Centrosomes define the poles of mitotic spindles, but spindles that lack centrosomes mediate meiotic chromosome segregation in females. Recent studies provide new insight into anastral-spindle assembly, and indicate that a conserved protein complex may be critical to the stability of both the astral- and anastral-spindle pole.

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Figure 1: Assembly of an anastral-spindle pole.

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  1. the Program in Molecular Medicine, University of Massachusetts Medical School, 373 Plantation Street, Worcester, 01605, Massachusetts, USA

    William E. Theurkauf

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  1. William E. Theurkauf
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Theurkauf, W. TACCing down the spindle poles. Nat Cell Biol 3, E159–E160 (2001). https://doi.org/10.1038/35083110

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