Skip to main content
Log in

Biological catalysis

The hairpin's turn

  • News & Views
  • Published:

From Nature

View current issue Submit your manuscript

A crystal structure of the hairpin ribozyme provides an atomic framework for understanding RNA catalysis, including features that may be common to both RNA and protein enzymes.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Figure 1: RNA and protein enzymes.

References

  1. Rupert, P. B. & Ferré-D'Amaré, A. R. Nature 410, 780–786 (2001).

    Article  ADS  CAS  Google Scholar 

  2. Steitz, T. A. & Steitz, J. A. Proc. Natl Acad. Sci. USA 90, 6498–6502 (1993).

    Article  ADS  CAS  Google Scholar 

  3. Nesbitt, S., Hegg, L. A. & Fedor, M. J. Chem. Biol. 4, 619–630 (1997).

    Article  CAS  Google Scholar 

  4. Murray, J. B., Seyhan, A. A., Walter, N. G., Burke, J. M. & Scott, W. G. Chem. Biol. 5, 587–595 (1998).

    Article  CAS  Google Scholar 

  5. Cai, Z. & Tinoco, I. Biochemistry 35, 6026–6036 (1996).

    Article  CAS  Google Scholar 

  6. Butcher, S. E., Allain, F. H. & Feigon, J. Nature Struct. Biol. 6, 212–216 (1999).

    Article  CAS  Google Scholar 

  7. Hampel, K. J. & Burke, J. M. Biochemistry (in the press).

  8. Richards, F. M. et al. Cold Spring Harb. Symp. Quant. Biol. 36, 35–43 (1971).

    Article  CAS  Google Scholar 

  9. Deavin, A., Mathias, A. P. & Rabin, B. R. Nature 211, 252–255 (1966).

    Article  ADS  CAS  Google Scholar 

  10. Ferré-D'Amaré, A. R., Zhou, K. & Doudna, J. A. Nature 395, 567–574 (1998).

    Article  ADS  Google Scholar 

  11. Nakano, S., Chadalavada, D. M. & Bevilacqua, P. C. Science 287, 1493–1497 (2000).

    Article  ADS  CAS  Google Scholar 

  12. Muth, G. W., Ortoleva-Donnelly, L. & Strobel, S. A. Science 289, 947–950 (2000).

    Article  ADS  CAS  Google Scholar 

  13. Nissen, P., Hansen, J., Ban, N., Moore, P. & Steitz, T. Science 289, 920–930 (2000).

    Article  ADS  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Scott A. Strobel.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Strobel, S., Ryder, S. The hairpin's turn. Nature 410, 761–762 (2001). https://doi.org/10.1038/35071209

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/35071209

  • Springer Nature Limited

Navigation