A crystal structure of the hairpin ribozyme provides an atomic framework for understanding RNA catalysis, including features that may be common to both RNA and protein enzymes.
References
Rupert, P. B. & Ferré-D'Amaré, A. R. Nature 410, 780–786 (2001).
Steitz, T. A. & Steitz, J. A. Proc. Natl Acad. Sci. USA 90, 6498–6502 (1993).
Nesbitt, S., Hegg, L. A. & Fedor, M. J. Chem. Biol. 4, 619–630 (1997).
Murray, J. B., Seyhan, A. A., Walter, N. G., Burke, J. M. & Scott, W. G. Chem. Biol. 5, 587–595 (1998).
Cai, Z. & Tinoco, I. Biochemistry 35, 6026–6036 (1996).
Butcher, S. E., Allain, F. H. & Feigon, J. Nature Struct. Biol. 6, 212–216 (1999).
Hampel, K. J. & Burke, J. M. Biochemistry (in the press).
Richards, F. M. et al. Cold Spring Harb. Symp. Quant. Biol. 36, 35–43 (1971).
Deavin, A., Mathias, A. P. & Rabin, B. R. Nature 211, 252–255 (1966).
Ferré-D'Amaré, A. R., Zhou, K. & Doudna, J. A. Nature 395, 567–574 (1998).
Nakano, S., Chadalavada, D. M. & Bevilacqua, P. C. Science 287, 1493–1497 (2000).
Muth, G. W., Ortoleva-Donnelly, L. & Strobel, S. A. Science 289, 947–950 (2000).
Nissen, P., Hansen, J., Ban, N., Moore, P. & Steitz, T. Science 289, 920–930 (2000).
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Strobel, S., Ryder, S. The hairpin's turn. Nature 410, 761–762 (2001). https://doi.org/10.1038/35071209
Issue Date:
DOI: https://doi.org/10.1038/35071209
- Springer Nature Limited