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Cell polarity: the PARty expands

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Recent work has revealed an evolutionarily conserved trio of proteins that regulate cell polarity in epithelial cells, embryonic blastomeres and neural precursors. This common cell-polarity mechanism is used in cell-specific ways, as highlighted by the recent finding that at least two different types of asymmetric division are observed in Drosophila neural precursors.

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Figure 1: The PAR-3–PAR-6–aPKC protein complex.
Figure 2: Two types of asymmetric division in the Drosophila cell lineage for external sense organs.

References

  1. Petronczki, M. & Knoblich, J. A. Nature Cell Biol. 3, 43–49 (2001 ).

    Article  CAS  Google Scholar 

  2. Wodarz, A., Ramrath, A., Grimm, A., & Knust, E. J. Cell Biol. 150, 1361–1374 (2000).

    Article  CAS  Google Scholar 

  3. Bellaiche, Y., Gho, M., Kaltschmidt, J. A., Brand, A. H. & Schweisguth, F. Nature Cell Biol. 3, 50–57 (2001 ).

    Article  CAS  Google Scholar 

  4. Roegiers, F., Younger-Shepard, S., Jan, L. & Jan, Y. N. Nature Cell Biol. 3, 58–67 (2001).

    Article  CAS  Google Scholar 

  5. Doe, C. Q. & Bowerman, B. Curr. Opin. Cell Biol. in the press.

  6. Kim, S. K. Nature Cell Biol. 2, E143–E145 (2000).

    Article  CAS  Google Scholar 

  7. Schober, M., Schaefer, M. & Knoblich, J. A. Nature 402, 548– 551 (1999).

    Article  CAS  Google Scholar 

  8. Bilder, D., Li. M. & Perrimon, N. Science 289, 113– 116 (2000).

    Article  CAS  Google Scholar 

  9. Legouis, R. et al. Nature Cell Biol. 2, 415– 422 (2000).

    Article  CAS  Google Scholar 

  10. Gho, M., Bellaiche, Y. & Schweisguth, F. Development 126, 3573– 3584 (1999).

    CAS  PubMed  Google Scholar 

  11. Kaltschmidt, J. A., Davidson, C. M., Brown, N. H. & Brand, A. H. Nature Cell Biol. 2, 7– 12 (2000).

    Article  CAS  Google Scholar 

  12. Kraut, R., Chia, W., Jan, L. Y., Jan, Y. N. & Knoblich, J. A. Nature 383, 50 –55 (1996).

    Article  CAS  Google Scholar 

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  1. the Institute of Molecular Biology and the Institute of Neuroscience, HHMI, University of Oregon, Eugene, 97403, Oregon, USA

    Chris Q. Doe

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  1. Chris Q. Doe
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Doe, C. Cell polarity: the PARty expands. Nat Cell Biol 3, E7–E9 (2001). https://doi.org/10.1038/35050684

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