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Developmental biology

Control by combinatorial codes

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Studies in fruitflies support the idea that regulatory regions of genes control development by acting as molecular 'computers', calculating cell fate according to the combined effects of several signalling pathways.

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Figure 1: Gene regulation by combinatorial logic.

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Correspondence to K. VijayRaghavan.

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Ghazi, A., VijayRaghavan, K. Control by combinatorial codes. Nature 408, 419–420 (2000). https://doi.org/10.1038/35044174

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