This is a preview of subscription content, log in via an institution to check access.
References
Matsuyama, S., Llopi, J., Deveraux, Q., Tsien, R. & Reed, J. Changes in intramitochondrial and cytosolic pH: early events that modulate caspase activation during apoptosis. Nature Cell Biol. 2, 318–325 (2000).
Boyarsky, G., Hanssen, C. & Clyne, L. A. Inadequacy of high K+/nigericin for calibrating BCECF II. Intracellular pH dependence of the correction. Am. J. Physiol. 271, C1146–C1156 (1996).
Boyarsky, G., Hanssen, C. & Clyne, L. A. Inadequacy of high K+/nigericin for calibrating BCECF I. Estimating steady-state intracellular pH. Am. J. Physiol. 271, C1131–C1145 (1996).
Hatefi, Y. ATP synthesis in mitochondria. Eur. J. Biochem. 218, 759–767 (1993).
Petronilli, V. et al. Imaging the mitochondrial permeability transition pore in intact cells. Biofactors 8, 263–272 (1998).
Rottenberg, H. & Wu, S. Quantitative assay by flow cytometry of the mitochondrial membrane potential in intact cells. Biochim. Biophys. Acta 1404, 393–404 (1998).
Vander Heiden, M., Chandel, N., Schumacker, P. & Thompson, C. Bcl-xl prevents cell death following growth factor withdrawal by facilitating mitochondrial ATP/ADP exchange. Mol. Cell 3, 159–167 (1999).
Barry, M. A. & Eastman, A. Endonuclease activation during apoptosis: the role of cytosolic Ca2+ and pH. Biochem. Biophys. Res. Comm. 186, 782–789 (1992).
Gottlieb, R., Nordberg, J., Skowronski, E. & Babior, B. Apoptosis induced in Jurkat cells by agents is preceded by intracellular acidification. Proc. Natl Acad. Sci. USA 93, 654–658 (1996).
Furlong, I. J., Ascaso, R., Lopez Rivas, A. & Collins, M. K. Intracellular acidification induces apoptosis by stimulating ICE-like protease activity. J. Cell Sci. 110, 653–661 (1997).
Chen, Q. et al. Role of acid/base homeostasis in the suppression of apoptosis in haemopoietic cells by v-Abl protein tyrosine kinase. J. Cell Sci. 110, 379–387 (1997).
Li, J. & Eastman, A. Apoptosis in an interleukin-2-dependent cytotoxic T lymphocyte cell line is associated with intracellular acidification. Role of the Na(+)/H(+)-antiport. J. Biol. Chem. 270, 3203–3211 (1995).
Thangaraju, M. et al. Regulation of acidification and apoptosis by SHP-1 and Bcl-2. J. Biol. Chem. 274, 29549–29557 (1999).
Asoh, S., Nishimaki, K., Nanbu-Wakao, R. & Ohta, S. A trace amount of the human pro-apoptotic factor Bax induces bacterial death accompanied by damage of DNA. J. Biol. Chem. 273, 11384–11391 (1998).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Reed, J., Matsuyama, S., Deveraux, Q. et al. Response. Nat Cell Biol 2, E172–E173 (2000). https://doi.org/10.1038/35036418
Issue Date:
DOI: https://doi.org/10.1038/35036418
- Springer Nature Limited