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It’s a kar9ochore to capture microtubules

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Abstract

Microtubule orientation to cortical spatial cues is essential for the fidelity of asymmetric cellular processes. A cortical microtubule-capture site, composed of Bim1 and Kar9, has now been identified in yeast. Bim1 is the yeast homologue of EB1, a binding partner of the adenomatous polyposis coli (APC), indicating that important features of this complex may be highly conserved.

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Figure 1: Microtubule dynamics and nuclear movement in yeast.

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Authors and Affiliations

  1. Department of Biology, 623 Fordham Hall, University of North Carolina, Chapel Hill, North Carolina, 27599, USA

    Kerry Bloom

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  1. Kerry Bloom
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Bloom, K. It’s a kar9ochore to capture microtubules. Nat Cell Biol 2, E96–E98 (2000). https://doi.org/10.1038/35014089

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