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mRNA export: the long and winding road

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Abstract

To the growing list of factors required for the export of messenger RNA from nucleus to cytoplasm can now be added Yra1. Yeast Yra1 and its metazoan orthologues bind mRNAs and interact with multiple mRNA export factors.Transport of proteins and small RNAs does not require Yra1 or any other proteins required for mRNA export, suggesting that mRNA export may proceed by a different mechanism. The finding that Yra1 has a role in mRNA export moves us one step closer to identifying all the proteins required for this process.

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Figure 1: Nucleocytoplasmic transport.

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  1. the Department of Biochemistry Dartmouth Medical School, Hanover, 03755, New Hampshire, USA

    Charles N. Cole

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  1. Charles N. Cole
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Cole, C. mRNA export: the long and winding road. Nat Cell Biol 2, E56–E58 (2000). https://doi.org/10.1038/35008681

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