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Spongiform encephalopathies

The prion's perplexing persistence

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Figure 1: Due to the species barrier between mice and hamsters, prions originating from one species produce spongiform encephalopathy rather quickly when transferred to a further animal of the same species, yet only produce disease — if any — with much longer latency when passed to the other species.

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Authors and Affiliations

  1. the Institute of Neuropathology, University Hospital of Zürich, CH-8091, Zürich, Switzerland

    Adriano Aguzzi

  2. the Institute of Molecular Biology, University of Zürich, Hönggerberg, 8093, Zürich, Switzerland

    Charles Weissmann

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  1. Adriano Aguzzi
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  2. Charles Weissmann
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Aguzzi, A., Weissmann, C. The prion's perplexing persistence. Nature 392, 763–764 (1998). https://doi.org/10.1038/33812

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