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Specific DNA amplification

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The polymerase chain reaction can synthesize millions of copies of a specific DNA sequence in a brief in vitro reaction. (Thermostable DNA polymerase from Thermus aquaticus improves the technique.)

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  1. H.A. Erlich: For more information, fill in reader service number 100.

Authors and Affiliations

  1. Departments of Human Genetics and Microbial Genetics, Cetus Corporation, 1400 Fifty-Third Street, Emeryville, California, 94608, USA

    H.A. Erlich, D.H. Gelfand & R.K. Saiki

Authors
  1. H.A. Erlich
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  2. D.H. Gelfand
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  3. R.K. Saiki
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Erlich, H., Gelfand, D. & Saiki, R. Specific DNA amplification. Nature 331, 461–462 (1988). https://doi.org/10.1038/331461a0

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