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Single-channel currents of an intercellular junction

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Abstract

We have used a double whole-cell patch-clamp system to make the first quantitative recordings of the single-channel current from an intercellular junction, presumably a gap junction. The junctional channel has various conductance states and discriminates poorly between cations and anions. It seems to change slowly from one conductance state to another.

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Authors and Affiliations

  1. Laboratoire de Neurobiologie, Ecole Normale Supérieure, 46 rue d'Ulm, 75005, Paris, France

    Jacques Neyton & Alain Trautmann

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  1. Jacques Neyton
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  2. Alain Trautmann
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Neyton, J., Trautmann, A. Single-channel currents of an intercellular junction. Nature 317, 331–335 (1985). https://doi.org/10.1038/317331a0

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  • DOI: https://doi.org/10.1038/317331a0

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