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A third rearranged and expressed gene in a clone of cytotoxic T lymphocytes

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Abstract

In addition to the two previously identified genes rearranged and expressed in a cytotoxic T-lymphocyte clone, we have identified a third gene that is also rearranged and expressed in the same clone. This new gene shows clonal diversity, codes for a polypeptide chain that contains immunoglobulin-like variable and constant domains, carries potential N-glycosylation sites and is a particularly attractive candidate for the gene that encodes the α-subunit of the heterodimeric antigen receptor of this T-cell clone.

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Saito, H., Kranz, D., Takagaki, Y. et al. A third rearranged and expressed gene in a clone of cytotoxic T lymphocytes. Nature 312, 36–40 (1984). https://doi.org/10.1038/312036a0

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  • DOI: https://doi.org/10.1038/312036a0

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