Skip to main content
SpringerLink
Log in

The ontogeny of the neural crest in avian embryo chimaeras

  • Review Article
  • Published:

From Nature

View current issue Submit your manuscript

Abstract

The migration and subsequent development of autonomie ganglion cell precursors can be followed in suitably constructed chimaeric quail–chick embryos, thanks to the distinctive structures of quail and chick interphase nuclei. The decisive role of environmental factors arising from non-neuronal tissues on the chemical differentiation of neurones was demonstrated together with the lability of their phenotype during ontogeny.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Vogt, W. Arch. Entw. Mech. 106, 542–610 (1925).

    Article  Google Scholar 

  2. Pasteels, J. Archs Biol. 48, 381–488 (1937).

    Google Scholar 

  3. Le Douarin, N. Bull. Biol. Fr. Belg. 103, 435–452 (1969).

    CAS  PubMed  Google Scholar 

  4. Hamburger, V. & Hamilton, H. L. J. Morph. 88, 49–92 (1951).

    Article  CAS  Google Scholar 

  5. Zacchei, A. M. Archs Anat. 66, 36–62 (1961).

    CAS  Google Scholar 

  6. Le Douarin, N. Expl Cell Res. 77, 459–468 (1973); Devl Biol. 30, 217–222 (1973); Med. Biol. 52, 281–319 (1974); Ciba Fdn Symp. 40, 71–101 (1976).

    Article  CAS  Google Scholar 

  7. Smith, J., Cochard, P. & Le Douarin, N. M. Cell Different. 6, 199–216 (1977).

    Article  CAS  Google Scholar 

  8. Jotereau, F. V. & Le Douarin, N. M. Devl. Biol. 63, 253–265 (1978).

    Article  CAS  Google Scholar 

  9. Le Douarin, N. M. & Rival, J. M. Devl. Biol. 47, 215–221 (1975).

    Article  CAS  Google Scholar 

  10. Hörstadius, S. in The Neural Crest: Its Properties and Derivatives in the Light of Experimental Research, 111 (Oxford University Press, London, 1950).

    Google Scholar 

  11. Weston, J. A. Adv. Morphogenesis 8, 41–114 (1970).

    Article  CAS  Google Scholar 

  12. Johnston, M. C., Bhakdinaronk, A. & Reid, Y. C. in Oral Sensation and Perception: Development in the Fetus and Infant (ed. Bosma, J. F.) (U.S. Govt. Printing Office, Washington, 1974).

    Google Scholar 

  13. Noden, D. M. Devl. Biol. 67, 296–312 (1978); 67, 313–329 (1978); in The Specificity of Embryological Interactions (ed. Garrod, D.), 4–49 (Chapman and Hall, London, 1978).

    Google Scholar 

  14. Le Lièvre, C. J. Embryol. exp. Morph. 31, 453–477 (1974); 47, 17–37 (1978).

    Google Scholar 

  15. Le Lièvre, C. & Le Douarin, N. J. Embryol. exp. Morph. 34, 124–154 (1975).

    Google Scholar 

  16. Le Douarin, N. & Le Lièvre, C. in Birth Defects (Excerpta Medica Intern. Congr. Ser. no. 432), (eds Littlefield, J. W. & de Grouchy, J.) 141–153 (1978).

    Google Scholar 

  17. Le Douarin, N. & Le Lièvre, C. C.r. hebd. Séanc. Acad. Sci., Paris 270, 2857–2860 (1970).

    CAS  Google Scholar 

  18. Le Douarin, N., Le Lièvre, C. & Fontaine, J. C.r. hebd. Séanc. Acad. Sci., Paris 275, 583–586 (1972).

    CAS  Google Scholar 

  19. Le Douarin, N. M. in Gut Hormones (ed. Bloom, S. R.) 49–56 (Churchill Livingstone, Edinburgh, 1978).

    Google Scholar 

  20. Weston, J. A. Devl. Biol. 6, 279–310 (1963).

    Article  CAS  Google Scholar 

  21. Falck, B. Acta physiol. scand. 56, Suppl. 197, 1–25 (1962).

    Article  Google Scholar 

  22. Le Douarin, N. & Teillet, M. A. J. Embryol. exp. Morph. 30, 31–48 (1973).

    CAS  PubMed  Google Scholar 

  23. Teillet, M. A. W. Roux'Arch. dev. Biol. 184, 251–268 (1978).

    Article  CAS  Google Scholar 

  24. Le Douarin, N. & Teillet, M. A. Devl. Biol. 41, 162–184 (1974).

    Article  CAS  Google Scholar 

  25. Le Douarin, N.M., Renaud, D., Teillet, M. A. & Le Douarin, G. H. Proc. natn. Acad. Sci. U.S.A. 72, 728–732 (1975).

    Article  ADS  CAS  Google Scholar 

  26. Teillet, M. A., Cochard, P. & Le Douarin, N. M. Zoon 6, 115–122 (1978).

    Google Scholar 

  27. Cohen, A. M. J. exp. Zool. 179, 167–182 (1972).

    Article  CAS  Google Scholar 

  28. Norr, S. C. Devl. Biol. 34, 16–38 (1973).

    Article  CAS  Google Scholar 

  29. Cochard, P., Goldstein, M. & Black, I. Proc. natn. Acad. Sci. U.S.A. 75, 2986–2990 (1978).

    Article  ADS  CAS  Google Scholar 

  30. Landmesser, L. & Pilar, G. J. Physiol., Lond. 222, 691–713 (1972).

    Article  CAS  Google Scholar 

  31. Landmesser, L. & Pilar, G. Fedn Proc. 37, 2016–2022 (1978).

    CAS  Google Scholar 

  32. Chiappinelli, V., Giacobini, E., Pilar, G. & Uchimura, H. J. Physiol., Lond. 257, 749–767 (1976).

    Article  CAS  Google Scholar 

  33. Le Douarin, N. M., Teillet, M. A., Ziller, C. & Smith, J. Proc. natn. Acad. Sci. U.S.A. 75, 2030–2034 (1978).

    Article  ADS  CAS  Google Scholar 

  34. Rothman, T. P., Gershon, M. D. & Holtzer, H. Devl. Biol. 65, 322–341 (1978).

    Article  CAS  Google Scholar 

  35. Patterson, P. H. & Chun, L. L. Y. Proc. natn. Acad. Sci. U.S.A. 71, 3607–3610 (1974).

    Article  ADS  CAS  Google Scholar 

  36. Patterson, P. H. & Chun, L. L. Y. Devl. Biol. 56, 263–280 (1977).

    Article  CAS  Google Scholar 

  37. Burton, H. & Bunge, R. P. Brain Res. 97, 157–162 (1975).

    Article  CAS  Google Scholar 

  38. Johnson, M. et al. Nature 262, 308–310 (1976).

    Article  ADS  CAS  Google Scholar 

  39. Patterson, P. H. A. Rev. Neurosci. 1, 1–17 (1978).

    Article  CAS  Google Scholar 

  40. Furshpan, E. J., MacLeish, P. R., O'Lague, P. H. & Potter, D. D. Proc. natn. Acad. Sci. U.S.A. 73, 4225–4229 (1978).

    Article  ADS  Google Scholar 

  41. Landis, S. C. Proc. natn. Acad. Sci. U.S.A. 73, 4220–4224 (1976).

    Article  ADS  CAS  Google Scholar 

  42. Greenberg, J. H. & Schrier, B. K. Devl. Biol. 61, 86–93 (1977).

    Article  CAS  Google Scholar 

  43. Cohen, A. M. Proc. natn. Acad. Sci. U.S.A. 74, 2899–2903 (1977).

    Article  ADS  CAS  Google Scholar 

  44. Ziller, C., Smith, J. H., Fauquet, J. H. & Le Douarin, N. M. Prog. Brain Res. 51, 59–74 (1979).

    Article  CAS  Google Scholar 

  45. Enemar, A., Falck, B. & Håkanson, R. Devl. Biol. 11, 268–283 (1965).

    Article  CAS  Google Scholar 

  46. Teitelman, G., Baker, H., Job, T. H. & Reis, D. J. Proc. natn. Acad. Sci. U.S.A. 76, 509–513 (1979).

    Article  ADS  CAS  Google Scholar 

  47. Smith, J., Fauquet, M., Ziller, C. & Le Douarin, N. Nature 282, 853–855 (1979).

    Article  ADS  CAS  Google Scholar 

  48. Narayanan, C. H. & Narayanan, Y. J. Embryol. exp. Morph. 47, 137–148.

  49. Walicke, P. A., Campenot, R. B. & Patterson, P. H. Proc. natn. Acad. Sci. U.S.A. 74, 5767–5771 (1977).

    Article  ADS  CAS  Google Scholar 

  50. Saxod, R. Devl. Biol. 32, 167–178 (1973).

    Article  CAS  Google Scholar 

  51. Narayanan, C. H. & Narayanan, Y. J. Embryol. exp. Morph. 43, 85–105 (1978).

    CAS  PubMed  Google Scholar 

  52. Jotereau, F. V. & Le Douarin, N. M. Devl. Biol. 63, 253–265 (1978).

    Article  CAS  Google Scholar 

  53. Houssaint, E., Belo, M. & Le Douarin, N. Devl. Biol. 53, 250–264 (1976).

    Article  CAS  Google Scholar 

  54. Le Douarin, N. in Differentiation of Normal and Neoplastic Hematopoietic Cells 5–31 (Cold Spring Harbor Laboratory, New York, 1978); in Mechanisms of Cell Change (eds Ebert, J. E. & Okada, T. S.) 293–326 (Wiley, New York, 1979).

    Google Scholar 

  55. Le Douarin, N. & Jotereau, F. Nature new Biol. 246, 25 (1973); J. exp. Med. 142, 17–40 (1975).

    Article  CAS  Google Scholar 

  56. Dieterlen-Lièvre, F. J. Embryol exp. Morph. 33, 607–619 (1975).

    PubMed  Google Scholar 

  57. Martin, C., Beaupain, D. & Dieterlen-Lièvre, F. Cell Differentiation 7, 115–130 (1978).

    Article  CAS  Google Scholar 

  58. Beaupain, D., Martin, C. & Dieterlen-Lièvre, F. Blood 53, 212–225 (1979).

    CAS  PubMed  Google Scholar 

  59. Kahn, A. J. & Simmons, D. J. Nature 258, 325–327 (1975).

    Article  ADS  CAS  Google Scholar 

  60. Gumpel-Pinot, M., Martin, C. & Croisille, Y. C.r. hebd. Séanc. Acad. Sci., Paris 272, 737–739 (1971).

    CAS  Google Scholar 

  61. Martin, C. J. Embryol. exp. Morph. 35, 485–498 (1976).

    Google Scholar 

  62. Gumpel-Pinot, M. C.r. hebd. Séanc. Acad. Sci., Paris 279, 1305–1308 (1974).

    CAS  Google Scholar 

  63. Christ, B., Jacob, H. J. & Jacob, M. Experientia 30, 1446–1449 (1974); 1449–1451 (1974); 34, 241–242; 514–516 (1978).

    Article  CAS  Google Scholar 

  64. Chevallier, A. J. Embryol. exp. Morph. 42, 275–292 (1977); W. Roux's Archiv. 184, 57–73 (1978); J. Embryol exp. Morph. 49, 73–88 (1979).

    Google Scholar 

  65. Chevallier, A. J., Kieny, M., Mauger, A. & Sengel, P. in Vertebrate Limb and Somite Morphogenesis (eds Ede, D. A., Hinchliffe, J. R. & Balls, M.) 421–432 (Cambridge University Press, 1977).

    Google Scholar 

  66. Dhouailly, D. & Kieny, M. Devl. Biol. 28, 162–175 (1972).

    Article  CAS  Google Scholar 

  67. Kieny, M. in Vertebrate Limb and Somite Morphogenesis (eds Ede, D. A., Hinchliffe, J. R. & Balls, M.) 87–103 (Cambridge University Press, 1977).

    Google Scholar 

  68. Kieny, M. & Pautou, M. P. W. Roux's Archiv. 179, 327–338 (1976); 183, 177–191 (1977).

    Article  Google Scholar 

  69. Saunders, J. W., Gasseling, M. T. & Errick, J. E. Devl. Biol. 50, 16–25 (1976).

    Article  Google Scholar 

  70. Vakaet, L. C.r. hebd. Séanc. Acad. Sci., Paris 167, 781–783 (1973); 1053–1055 (1973); Année. Biol. 13, 35–41 (1974).

    CAS  Google Scholar 

  71. Hornbruch, A., Summerbell, D. & Wolpert, L. J. Embryol. exp. Morph. 51, 51–62 (1979).

    CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Institut d'Embryologie du CNRS et du Collège de France, 49bis, avenue de la Belle-Gabrielle, 94130, Nogent-sur-Marne, France

    Nicole M. Le Douarin

Authors
  1. Nicole M. Le Douarin
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Le Douarin, N. The ontogeny of the neural crest in avian embryo chimaeras. Nature 286, 663–669 (1980). https://doi.org/10.1038/286663a0

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/286663a0

  • Springer Nature Limited

This article is cited by

Search

Navigation