Abstract
SINCE the report by Simantov et al.1 invertebrates have been thought to lack endogenous opiates and opiate receptors. As we have previously observed peptidergic neurones containing immunoreactive pancreatic polypeptide or vasoactive intestinal peptide in the earthworm2, we decided to search for, and report here our finding of, nerves storing immunoreactive enkephalin or β-endorphin in this species.
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References
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ALUMETS, J., HÅKANSON, R., SUNDLER, F. et al. Neuronal localisation of immunoreactive enkephalin and β-endorphin in the earthworm. Nature 279, 805–806 (1979). https://doi.org/10.1038/279805a0
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DOI: https://doi.org/10.1038/279805a0
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