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Nucleotide sequence of cloned cDNA for bovine corticotropin-β-lipotropin precursor

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Abstract

The nucleotide sequence of a 1,091-base pair cloned cDNA insert encoding bovine corticotropin-β-lipotropin precursor mRNA is reported. The corresponding amino acid sequence indicates that the precursor protein consists of repetitive units and includes a third melanotropin sequence in its cryptic portion. Pairs of lysine and arginine residues separate the component peptides of the precursor.

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Authors and Affiliations

  1. Department of Medical Chemistry, Kyoto University Faculty of Medicine, Kyoto, 606, Japan

    Shigetada Nakanishi, Akira Inoue, Toru Kita, Akira Inoue, Masahiro Nakamura & Shosaku Numa

  2. Departments of Genetics and Medicine, Stanford University School of Medicine, Stanford, California, 94305

    Annie C. Y. Chang & Stanley N. Cohen

Authors
  1. Shigetada Nakanishi
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  2. Akira Inoue
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  3. Toru Kita
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  4. Akira Inoue
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  5. Masahiro Nakamura
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  6. Annie C. Y. Chang
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  7. Stanley N. Cohen
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  8. Shosaku Numa
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Nakanishi, S., Inoue, A., Kita, T. et al. Nucleotide sequence of cloned cDNA for bovine corticotropin-β-lipotropin precursor. Nature 278, 423–427 (1979). https://doi.org/10.1038/278423a0

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  • DOI: https://doi.org/10.1038/278423a0

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