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Muscular fatigue investigated by phosphorus nuclear magnetic resonance

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Abstract

Muscular fatigue has been studied using 31P NMR to measure the levels and rates of utilisation of several key metabolites and the free-energy change for ATP hydrolysis. Force development is closely correlated with metabolite levels and is proportional to the rate at which ATP is hydrolysed.

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Authors and Affiliations

  1. Department of Physiology, University College London, Gower Street, London, WC1

    M. Joan Dawson, D. G. Gadian & D. R. Wilkie

  2. Department of Biochemistry, University of Oxford, Oxford, UK

    M. Joan Dawson

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  1. M. Joan Dawson
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  2. D. G. Gadian
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  3. D. R. Wilkie
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Joan Dawson, M., Gadian, D. & Wilkie, D. Muscular fatigue investigated by phosphorus nuclear magnetic resonance. Nature 274, 861–866 (1978). https://doi.org/10.1038/274861a0

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