Skip to main content

Advertisement

Log in

Cultivation of malarial parasites

  • Review Article
  • Published:

From Nature

View current issue Submit your manuscript

Abstract

The method for continuous cultivation of Plasmodium falciparum has now been successfully applied to several strains from different geographical areas. It has been used for tests of antimalarial drugs, for studies of parasite–host cell interactions with special reference to sickle haemoglobin, and for the production of amounts of parasite material sufficient for experimental immunisation of Aotus trivirgatus monkeys.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Developments in Malaria Immunology, Tech. Rep. Ser. Wld Hlth Org. 579 (1975).

  2. Beaudoin, R. L. Bull. Wld Hlth Org. 55, 373–376 (1977).

    CAS  Google Scholar 

  3. Vanderberg, J. J., Weiss, M. M. & Mack, S. R. Bull. Wld Hlth Org. 55, 377–392 (1977).

    CAS  Google Scholar 

  4. Trager, W. & Jensen, J. B. Science 193, 673–675 (1976).

    Article  ADS  CAS  Google Scholar 

  5. Jensen, J. B. & Trager, W. J. Parasit. 63, 883–886 (1977).

    Article  CAS  Google Scholar 

  6. Trager, W. Conference on Tropical Medicine, London, 1977 (Royal Society of Medicine, London, in the press).

  7. Jensen, J. B. & Trager, W. Am. J. trop. Med. Hyg. (in the press).

  8. Allison, A. C. Ann. N.Y. Acad. Sci. 91, 710–729 (1961).

    Article  ADS  CAS  Google Scholar 

  9. Siddiqui, W. A. Science 197, 388–389 (1977).

    Article  ADS  CAS  Google Scholar 

  10. Carter, R. & Beach, R. F. Nature 270, 240–241 (1977).

    Article  ADS  CAS  Google Scholar 

  11. Trager, W., Robert-Gero, M. & Lederer, E. FEBS Lett. 85, 264–266 (1978).

    Article  CAS  Google Scholar 

  12. Friedman, M. Proc. natn. Acad. Sci. U.S.A. (in the press).

  13. Pasvol, G., Weatherall, D. J. & Wilson, R. J. M. Nature 270, 171–173 (1977).

    Article  ADS  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Trager, W., Jenson, J. Cultivation of malarial parasites. Nature 273, 621–622 (1978). https://doi.org/10.1038/273621a0

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/273621a0

  • Springer Nature Limited

This article is cited by

Navigation