Abstract
UNTIL recently, the only accepted theory of powder mixing was based on a statistical randomisation of non-cohesive particles1. The introduction of the concept of ordered mixing2 enables a logical theory to be established for the mixing of small cohesive particles to a considerable degree of homogeneity. The concept of ordered mixing has attracted considerable support3–5. A basic principle of ordered mixing is that fine particles will adhere, especially to larger particles. The adhesional forces involved may be electrostatic or surface tensional. For a homogeneous system to be formed, the weight of fine particles adhering to unit surface area of the larger particles should be constant. We report here such a condition in the mixing of a fluid energy milled closely sized fraction (2.6 µm) of salicylic acid with a multi-sized distribution of sucrose crystals, in the ratio 1 : 1,000 by weight.
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YIP, C., HERSEY, J. Ordered powder mixing. Nature 262, 202–203 (1976). https://doi.org/10.1038/262202a0
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DOI: https://doi.org/10.1038/262202a0
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