Abstract
RHODOPSIN is a carotenoid-protein, in which the 11-cis retinal chromophore, is coupled to the colourless protein, opsin. The linkage between them is a protonated Schiff base between the aldehyde group of 11-cis retinal and an ε-amino group of L-lysine in opsin1–4.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Bownds, D., Nature, 216, 1178–1181 (1967).
Fager, R. S., Sejnowski, P., and Abrahamson, E. W., Biochem. biophys. Res. Commun., 41, 1244–1246 (1972).
De Grip, W. J., Bonting, S. L., and Daemen, F. J. M., Biochim. biophys. Acta, 303, 189–193 (1973).
Oseroff, A. R., and Callender, R. H., Biochemistry, 13, 4243–4248 (1974).
Blatz, P., Lin, M., Balasubramaniyan, P., Balasubramaniyan, V., and Dewhurst, P. B., J. Am. chem. Soc., 91, 5930–5931 (1969).
Hubbard, R., Brown, P. K., and Bownds, D., in Methods in Enzymology, 18, (edit. by McCormic, D. B., and Wright, L. D.), 615–653 (Academic, New York 1971).
Wald, G., and Brown, P. K., Nature, 177, 174–176 (1956).
Sperling, W., in Biochemistry and Physiology of Visual Pigments, (edit. by Langer, H.), 19–28 (Springer, Berlin, Heidelberg, New York, 1973).
Wald, G., Brown, P. K., and Smith, P. H., J. gen. Physiol., 38, 328–381 (1955).
Bownds, D., and Wald, G., Nature, 205, 254–257 (1965).
Matsumoto, H., Tokunaga, F., and Yoshizawa, T., Biochim. biophys. Acta, 404, 300–308 (1975).
Wald, G., and Hubbard, R., in The Enzymes, second ed., 3, 369–386, (Academic, New York, 1967).
Nelson, R., deRiel, J. K., and Kropf, A., Proc. natn. Acad. Sci., U.S.A., 66, 531–538 (1970).
Kropf, A., Whittenberger, B. P., Goff, S. P., and Waggoner, A. S., Expl Eye Res., 17, 591–606 (1973).
Blatz, P., Dewhurst, P. B., Balasubramaniyan, V., Barasubramaniyan, P., and Lin, M., Photochem. Photobiol., 11, 1–15 (1970).
Chan, W. K., Nakanishi, K., Ebrey, T. G., and Honig, B., J. Am. chem. Soc., 96, 3642–3644 (1974).
Curtis, M. J., Pitt, G. A. J., and Howell, J. McC., cited in Morton, R. A., and Pitt, G. A. J., Advances in Enzymology, 32, 97–171 (Interscience, New York, 1969).
Lewin, D. R., and Thompson, J. N., Biochem. J., 103, 36p (1967).
Wald, G., Fedn Proc., 12, 606 (1953).
Houghton, S. E., Lewin, D. R., and Pitt, G. A. J., cited in Morton, R. A., and Pitt, G. A. J., Advances in Enzymology, 32, 97–171 (Interscience, New York, 1969).
Azuma, M., Azuma, K., and Kito, Y., Biochim. biophys. Acta, 295, 520–527 (1973).
Wald, G., Expl Eye Res., 18, 333–343 (1974).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
MATSUMOTO, H., YOSHIZAWA, T. Existence of a β-ionone ring-binding site in the rhodopsin molecule. Nature 258, 523–526 (1975). https://doi.org/10.1038/258523a0
Received:
Accepted:
Issue Date:
DOI: https://doi.org/10.1038/258523a0
- Springer Nature Limited
This article is cited by
-
Molecular mechanisms of visual excitation: A concatenation of nonlinear cellular processes
Journal of Statistical Physics (1985)
-
Activation of phosphodiesterase by rhodopsin and its analogues
Biophysics of Structure and Mechanism (1983)
-
Hydrophobic bond energy of non-polar molecules: Application to ?-ionone and 11-cis retinal
Biophysics of Structure and Mechanism (1980)
-
Molecular mechanism for the initial process of visual excitation. IV. Energy surfaces of visual pigments and photoisomerization mechanism
Biophysics of Structure and Mechanism (1979)