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Evidence for Hb Lepore-like hybrid globin β chain genes in mice

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Abstract

WE have described structural data for mouse and rabbit embryonic β-like ε chains and the conclusions which can be drawn with respect to the evolution of ε globin chain genes in both species1. Here we present evidence for crossover events in the ancestral mouse β and ε-type chain genes leading to Hb Lepore-like globin chain genes which are functional in mice of recent evolutionary origin.

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Authors and Affiliations

  1. Max-Planck-Institut für experimentelle Medizin, Abteilung Molekulare Biologie, Hermann-Rein-Strasse 3, D 3400, Göttingen, FDR

    G. STEINHEIDER, H. MELDERIS & W. OSTERTAG

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  1. G. STEINHEIDER
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  2. H. MELDERIS
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  3. W. OSTERTAG
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STEINHEIDER, G., MELDERIS, H. & OSTERTAG, W. Evidence for Hb Lepore-like hybrid globin β chain genes in mice. Nature 257, 712–714 (1975). https://doi.org/10.1038/257712a0

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  • DOI: https://doi.org/10.1038/257712a0

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