Abstract
INSECTS are the only invertebrate animals which have been shown to possess a well developed blood–brain barrier. This barrier limits the rate of intercellular diffusion of water-soluble substances between the blood and the fluid layer which is the immediate environment of the nerve cells (see ref. 1). It has been proposed that this limitation results from the presence of intercellular occlusions, notably tight junctions, in the cellular layer of the nerve sheath, the perineurium (Fig. 1).
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SCHOFIELD, P., TREHERNE, J. Sodium transport and lithium movements across the insect blood–brain barrier. Nature 255, 723–725 (1975). https://doi.org/10.1038/255723a0
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DOI: https://doi.org/10.1038/255723a0
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