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Immunisation of marmoset monkeys with a killed oncogenic herpesvirus

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Abstract

HERPESVIRUSES are suspected to be causal agents in human malignant neoplasia. At the present level of knowledge, clinical trials in man with viral vaccines against oncogenic herpesviruses cannot be initiated, but the oncogenic herpesviruses derived from monkeys1,2 can be used in vivo to study the problems of herpesvirus cancer vaccines. The oncogenic herpesvirus saimiri (HVS) regularly induces malignant lymphoma in cotton topped (CT) marmoset monkeys (S. oedipus). A killed vaccine from HVS was developed in our laboratory and tested for safety and efficacy in this primate model system.

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Authors and Affiliations

  1. Hygiene-Institut der Universität, Göttingen, D-34, West Germany

    R. LAUFS

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  1. R. LAUFS
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LAUFS, R. Immunisation of marmoset monkeys with a killed oncogenic herpesvirus. Nature 249, 571–572 (1974). https://doi.org/10.1038/249571a0

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  • DOI: https://doi.org/10.1038/249571a0

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