Abstract
THE rhinoviruses comprise a subgroup of the picornaviruses, distinguished by their acid lability. They are medically important as the infectious agents of the common cold in man. Although there have been reports of chemical agents which inhibit rhinovirus replication, in only a few instances has the mode of antiviral action been demonstrated at a biochemical level1,2.
Similar content being viewed by others
References
Schleicher, J. B., Aquino, F. A., Rueter, A., Roderick, W. R., and Appell, R. N., Abstr. Tenth Interscience Conf. Antimicrobial Agents and Chemotherapy, Chicago, Abstr. No. 99 (1970).
Matsumoto, S., Stanfield, F. J., Goore, M. Y., and Haff, R. F., Proc. Soc. exp. biol. Med., 139, 455 (1972).
Vallee, B. L.,and Wacker, W. E. C., in The Proteins (edit. by Neurath, H.), 5, No. 22, 143 (Academic Press, New York, 1972).
Hughes, M. N., The Inorganic Chemistry of Biological Processes (Wiley, London, 1972).
Korant, B. D., Lonberg-Holm, K., Noble, J., and Stasny, J. T., Virology, 48, 71 (1972).
Medappa, K. C., McLean, C., and Rueckert, R. R., Virology, 44, 259 (1971).
McLean, C., and Rueckert, R. R., J. Virol., 11, 341 (1973).
Butterworth, B. E., Virology, 56, 439 (1973).
Reviewed by Sugiyama, T., Korant, B. D., and Lonberg-Holm, K. K., A. Rev. Microbiol., 26, 467 (1972).
Laemmli, U. K., Nature, 227, 680 (1970).
Vogt, V. M., and Eisenman, R., Proc. natn. Acad., Sci. U.S.A., 70, 1734 (1973).
Korant, B. D., J. Virol., 10, 751 (1972).
Summers, D. F., Shaw, E., Stewart, M. L.,and Maizel, J. V., J. Virol., 10, 880 (1972).
Korant, B. D., J. Virol., 12, 556 (1973).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
KORANT, B., KAUER, J. & BUTTERWORTH, B. Zinc ions inhibit replication of rhinoviruses. Nature 248, 588–590 (1974). https://doi.org/10.1038/248588a0
Received:
Issue Date:
DOI: https://doi.org/10.1038/248588a0
- Springer Nature Limited
This article is cited by
-
Nanostructures for prevention, diagnosis, and treatment of viral respiratory infections: from influenza virus to SARS-CoV-2 variants
Journal of Nanobiotechnology (2023)
-
Functional Fiber Membranes with Antibacterial Properties for Face Masks
Advanced Fiber Materials (2023)
-
Combination therapy of zinc and trimethoprim inhibits infection of influenza A virus in chick embryo
Virology Journal (2021)
-
Can Zn Be a Critical Element in COVID-19 Treatment?
Biological Trace Element Research (2021)
-
Protective hybrid coating containing silver, copper and zinc cations effective against human immunodeficiency virus and other enveloped viruses
BMC Microbiology (2016)