Abstract
MAREK'S disease (MD) is a lymphoproliferative disease of chickens which is generally considered to be neoplastic1. It is probably the most commonly occurring neoplasm of any animal and until recently it caused extensive economic loss, estimated to be in excess of 150 million dollars annually, to the poultry industry2. Several viral vaccines which will effectively prevent the disease have been developed3 and the most extensively used is a herpesvirus isolated from turkeys (HVT)4, which will prevent the disease in laboratory and field trials5,6.
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PURCHASE, H., SHARMA, J. Amelioration of Marek's disease and absence of vaccine protection in immunologically deficient chickens. Nature 248, 419–421 (1974). https://doi.org/10.1038/248419a0
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DOI: https://doi.org/10.1038/248419a0
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