Skip to main content
SpringerLink
Log in

Temperature-sensitive Mammalian Cell Line Blocked in Mitosis

  • Letter
  • Published:

From Nature

View current issue Submit your manuscript

Abstract

SEVERAL temperature-sensitive mammalian cell mutants in culture have been isolated1–10, including three defective in protein syntheses6, cytokinesis5 and the processing of ribosomal RNA10, respectively. I have now isolated a hamster cell mutant in which mitosis is blocked in metaphase.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Naha, P. M., Nature, 223, 1380 (1969).

    Article  ADS  CAS  Google Scholar 

  2. Thompson, L. H., Mankovitz, R., Baker, R. M., Till, J. E., Siminovitch, L., and Whitmore, G. F., Proc. natn. Acad. Sci. U.S.A., 66, 377 (1970).

    Article  ADS  CAS  Google Scholar 

  3. Thompson, L. H., Mankovitz, R., Baker, R. M., Wright, J. A., Till, J. E., Siminovitch, L., and Whitmore, G. F., J. Cell Physiol., 78, 431 (1971).

    Article  CAS  Google Scholar 

  4. Meiss Harriet, K., and Basilico, C., Nature new Biol., 239, 66 (1972).

    Article  Google Scholar 

  5. Smith, B. J., and Wigglesworth, N. M., J. cell. Physiol., 80, 253 (1972).

    Article  CAS  Google Scholar 

  6. Thompson, L. H., and Stanners, C. P., J. Cell Biol., 55, 260a (1972).

    Google Scholar 

  7. Naha, P. M., Nature new Biol., 241, 13 (1973).

    Article  CAS  Google Scholar 

  8. Scheffler, I. E., and Buttin, G., J. cell. Physiol., 81, 199 (1973).

    Article  CAS  Google Scholar 

  9. Smith Diana, B., and Chu, E. H. Y., Mutation Res., 17, 113 (1973).

    Article  Google Scholar 

  10. Toniolo, D., Meiss, H. K., and Basilico, C., Proc. natn. Acad. Sci. U.S.A., 70, 1273 (1973).

    Article  ADS  CAS  Google Scholar 

  11. Rueckert, R. R., and Meuller, G., Cancer Res., 20, 1584 (1960).

    CAS  PubMed  Google Scholar 

  12. Prescott, D. M., and Bender, M. A., Expl Cell Res., 26, 260 (1962).

    Article  Google Scholar 

  13. Eigsti, O. J., and Dustin, jun., P., Colchicine—in Agriculture, Medicine, Biology and Chemistry (Iowa State College Press, Ames, 1955).

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Division of Biological Sciences, University of Missouri-Columbia, Columbia, Missouri, 65201

    RICHARD J. WANG

Authors
  1. RICHARD J. WANG
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

WANG, R. Temperature-sensitive Mammalian Cell Line Blocked in Mitosis. Nature 248, 76–78 (1974). https://doi.org/10.1038/248076a0

Download citation

  • Received:

  • Revised:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/248076a0

  • Springer Nature Limited

This article is cited by

Search

Navigation