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Recovery of Yeast from Transient Inhibition of DNA Synthesis

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Abstract

IN the simple eukaryotic cell Saccharomyces cerevisiae nuclear division, cell division and the start of new budding cycles depend on DNA synthesis1. Protein synthesis is required for the recovery of new budding and cell division after transient exposure to hydroxyurea, a specific reversible inhibitor of DNA synthesis2. In this report I have attempted to answer two questions. (1) Does recovery of nuclear division require protein synthesis? (2) Does recovery of DNA synthesis itself require protein synthesis?

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Authors and Affiliations

  1. Department of Molecular Biology and Microbiology, Tufts University School of Medicine, Boston, Massachusetts, 02111

    M. L. SLATER

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  1. M. L. SLATER
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SLATER, M. Recovery of Yeast from Transient Inhibition of DNA Synthesis. Nature 247, 275–276 (1974). https://doi.org/10.1038/247275a0

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  • DOI: https://doi.org/10.1038/247275a0

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