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Evolution of Ribonuclease in Relation to Polypeptide Folding Mechanisms

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Abstract

Sequences from seven pancreatic RNAases show a highly variable structure. The evolution of apparently functionless parts of a protein is thought to be based upon requirements for the polypeptide folding process.

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References

  1. Smith, E. L., in The Enzymes, third edition, (edit. by Boyer P. D.), 1, 267 (Academic Press, New York, 1970).

    Google Scholar 

  2. Fitch, W. M., J. Mol. Evol., 1, 84 (1971).

    Article  ADS  CAS  Google Scholar 

  3. Dickerson, R. E., J. Mol. Evol., 1, 26 (1971).

    Article  ADS  CAS  Google Scholar 

  4. Perutz, M. F., Kendrew, J. C., and Watson, H. C., J. Mol. Biol., 13, 669 (1965).

    Article  CAS  Google Scholar 

  5. King, J. L., and Jukes, T. H., Science, 164, 788 (1969).

    Article  ADS  CAS  Google Scholar 

  6. Kimura, M., Proc. US Nat. Acad. Sci., 63, 1181 (1969).

    Article  ADS  CAS  Google Scholar 

  7. Lanks, K. W., and Kitchin, F. S., Nature, 226, 753 (1970).

    Article  ADS  CAS  Google Scholar 

  8. Clarke, B., Science, 168, 1009 (1970).

    Article  ADS  CAS  Google Scholar 

  9. Richmond, R. C., Nature, 225, 1025 (1970).

    Article  ADS  CAS  Google Scholar 

  10. Barnard, E. A., Nature, 221, 340 (1969).

    Article  ADS  CAS  Google Scholar 

  11. Barnard, E. A., Ann. Rev. Biochem., 38, 677 (1969).

    Article  CAS  Google Scholar 

  12. Smyth, D. G., Stein, W. H., and Moore, S., J. Biol. Chem., 238, 227 (1963).

    CAS  PubMed  Google Scholar 

  13. Kartha, G., Bello, J., and Harker, D., Nature, 213, 862 (1965).

    Article  ADS  Google Scholar 

  14. Richards, F. M., and Wyckoff, H. W., in The Enzymes, third edition (edit. by Boyer, P. D.), 4, 647 (Academic Press, New York, 1971).

    Google Scholar 

  15. Jackson, R. L., and Hirs, C. H. W., J. Biol. Chem., 245, 637 (1970).

    CAS  PubMed  Google Scholar 

  16. Beintema, J. J., and Gruber, M., Biochim. Biophys. Acta, 147, 612 (1967).

    Article  CAS  Google Scholar 

  17. Edman, P., and Begg, G., Eur. J. Biochem., 1, 80 (1967).

    Article  CAS  Google Scholar 

  18. Jeppsonn, J. O., and Sjoquist, J., Anal. Biochem., 18, 264 (1967).

    Article  Google Scholar 

  19. Corbin, K. W., and Uzzell, T., Amer. Nat., 104, 37 (1970).

    Article  CAS  Google Scholar 

  20. Ohta, T., and Kimura, M., Nature, 233, 118 (1971).

    Article  ADS  CAS  Google Scholar 

  21. Eaker, D. L., King, T. P., and Craig, L. C., Biochemistry, 4, 1486 (1965).

    Article  CAS  Google Scholar 

  22. Marchiori, F., Borin, G., Moroder, L., Rocchi, R., and Scoffone, E., Biochim. Biophys. Acta, 257, 210 (1972).

    Article  CAS  Google Scholar 

  23. Hofmann, K., Andreata, R., Finn, F. M., Montibeller, J., Porcelli, G., and Quattrone, A. J., Bioorg. Chem., 1, 66 (1971).

    Article  CAS  Google Scholar 

  24. Rocchi, R., Scatturin, A., Moroder, L., Marchiori, F., Tamburro, A. M., and Scoffone, E., J. Amer. Chem. Soc., 91, 492–3927 (1969).

    Article  CAS  Google Scholar 

  25. Vithayathil, P. J., and Richards, F. M., J. Biol. Chem., 234, 1459 (1959).

    PubMed  Google Scholar 

  26. Klee, W. A., J. Biol. Chem., 240, 2900 (1965).

    CAS  PubMed  Google Scholar 

  27. Potts, J. T., Young, D. M., and Anfinsen, C. B., J. Biol. Chem., 238, 2593 (1963).

    PubMed  Google Scholar 

  28. Gutte, B., and Merrifield, R. B., Fed. Proc., 29, 727 (1970).

    Google Scholar 

  29. Doolittle, R. F., quoted in Arnheim, N., and Taylor, C. E., Nature, 223, 900 (1969).

    Article  ADS  Google Scholar 

  30. Friedman, M. E., Scheraga, H. A., and Goldberger, R. F., Biochemistry, 5, 3770 (1966).

    Article  CAS  Google Scholar 

  31. Lewis, P. N., Momany, F. A., and Scheraga, H. A., Proc. US Nat. Acad. Sci., 68, 2293 (1971).

    Article  ADS  CAS  Google Scholar 

  32. De Coen, J. L., J. Mol. Biol., 49, 405 (1970).

    Article  CAS  Google Scholar 

  33. Tanford, C., Adv. Protein Chem., 24, 1 (1969).

    Google Scholar 

  34. Epstein, C. J., Nature, 215, 355 (1967).

    Article  ADS  CAS  Google Scholar 

  35. Wyckoff, H. W., Brookhaven Symp. Biol., 21, 252 (1968).

    Google Scholar 

  36. Kato, I., and Anfinsen, C. B., J. Biol. Chem., 244, 1004 (1969).

    CAS  PubMed  Google Scholar 

  37. Epstein, C. J., and Goldberger, R. F., J. Biol. Chem., 239, 1087 (1964).

    CAS  PubMed  Google Scholar 

  38. Frensdorff, A., Wilchek, M., and Sela, M., Eur. J. Biochem., 1, 281 (1967).

    Article  CAS  Google Scholar 

  39. Nishikawa, A. H., Morita, R. Y., and Becker, R. B., Biochemistry, 7, 1506 (1968).

    Article  CAS  Google Scholar 

  40. Oyer, P. E., Cho, S., Peterson, J. D., and Steiner, D. F., J. Biol. Chem., 246, 1375 (1971).

    CAS  PubMed  Google Scholar 

  41. Taniuchi, H., J. Biol. Chem., 245, 5459 (1970).

    CAS  PubMed  Google Scholar 

  42. Canfield, R. E., Kammeman, S., Sobel, J. H., and Morgan, F. J., Nature New Biology, 232, 16 (1971).

    Article  CAS  Google Scholar 

  43. Hermann, J., and Jollès, J., Biochim. Biophys. Acta, 200, 178 (1970).

    Article  CAS  Google Scholar 

  44. La Rue, J., and Speck, J. C., J. Biol. Chem., 245, 1985 (1970).

    CAS  Google Scholar 

  45. Kaneda, M., Kato, I., Tominaga, N., Titani, K., and Narita, K., J. Biochem., 66, 747 (1969).

    CAS  PubMed  Google Scholar 

  46. Blake, C. C. F., and Swan, I. D. A., Nature, 232, 12 (1971).

    CAS  Google Scholar 

  47. Moon, K., Piszkiewicz, D., and Smith, E. L., Proc. US Nat. Acad. Sci., 69, 1380 (1972).

    Article  ADS  CAS  Google Scholar 

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Author notes

  1. M. H. GOLD

    Present address: Department of Biochemistry, University of California, Davis, California, 95616

Authors and Affiliations

  1. Department of Biochemistry, State University of New York, Buffalo, New York, 14214

    E. A. BARNARD, MARY S. COHEN, M. H. GOLD & JAE-KYOUNG KIM

Authors
  1. E. A. BARNARD
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  2. MARY S. COHEN
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  3. M. H. GOLD
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  4. JAE-KYOUNG KIM
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BARNARD, E., COHEN, M., GOLD, M. et al. Evolution of Ribonuclease in Relation to Polypeptide Folding Mechanisms. Nature 240, 395–398 (1972). https://doi.org/10.1038/240395a0

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  • DOI: https://doi.org/10.1038/240395a0

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