Skip to main content
SpringerLink
Log in

Natural Selection and Genetic Drift in Protein Polymorphism

  • Letter
  • Published:

From Nature

View current issue Submit your manuscript

Abstract

THE Kimura theory1 that protein polymorphism is mainly due to random genetic drift acting on a number of neutral isoalleles has been recently discussed by many authors2–4. The electrophoretic study of populations of the same species having different geographical origin and showing great fluctuations in number offers possibilities for testing the relative importance of natural selection and genetic drift in the context. We report a study of two species of mosquitoes, Aedes aegypti and Aedes mariae, for the phosphoglucomutase (PGM) locus. This is an autosomal locus belonging in A. aegypti to the linkage group 2 and showing in both species a very high number of electrophoretically detectable alleles (Bullini et al., refs. 5 and 6, and unpublished data).

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Kimura, M., Nature, 217, 624 (1968).

    Article  ADS  CAS  PubMed  Google Scholar 

  2. Prakash, S., Lewontin, R. C., and Hubby, J. L., Genetics, 61, 841 (1969).

    CAS  PubMed  PubMed Central  Google Scholar 

  3. Kimura, M., and Ohta, T., Nature, 229, 467 (1971).

    Article  ADS  CAS  PubMed  Google Scholar 

  4. Bulmer, M. G., Nature, 234, 410 (1971).

    Article  ADS  CAS  PubMed  Google Scholar 

  5. Bullini, L., Coluzzi, M., Gironi, A. M., and Morellini, M., Parassitologia, 12, 27 (1970).

    Google Scholar 

  6. Bullini, L., Gironi, A. M., Bianchi Bullini, A. P., and Coluzzi, M., Biochemical Genetics (in the press).

  7. Coluzzi, M., and Bullini, L., Nature, 231, 455 (1971).

    Article  ADS  CAS  PubMed  Google Scholar 

  8. Coluzzi, M., Bullini, L., and Bianchi Bullini, A. P., Biochemical Genetics, 5, 253 (1971).

    Article  CAS  PubMed  Google Scholar 

  9. Coluzzi, M., Bullini, L., and Bianchi Bullini, A. P., Bull. Ent. Res., 61, 327 (1971).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Istituto di Genetica, Universitá di Roma,

    LUCIANO BULLINI

  2. Istituto di Parassitologia, Universitá di Roma,

    MARIO COLUZZI

Authors
  1. LUCIANO BULLINI
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. MARIO COLUZZI
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

BULLINI, L., COLUZZI, M. Natural Selection and Genetic Drift in Protein Polymorphism. Nature 239, 160–161 (1972). https://doi.org/10.1038/239160a0

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1038/239160a0

  • Springer Nature Limited

This article is cited by

Search

Navigation