Skip to main content

Advertisement

Log in

A Prototype Live Oral Cholera Vaccine

  • Article
  • Published:

From Nature

View current issue Submit your manuscript

Abstract

Using the methods of molecular genetics it should be possible to develop a cholera vaccine that produces long lasting immunity. To this end Vibrio cholerae mutants deficient in choleragenic activity have been isolated.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Mosley, W. H., Tex. Rep. Biol. Med., 27, 227 (1969).

    Google Scholar 

  2. Mosley, W. H., McCormack, W. M., Fahimuddin, M., Aziz, K. M. A., Rahman, A. S. M. M., Chowdhury, A. K. M. A., Martin, A. R., Feeley, J. C., and Phillips, R. A., Bull. WHO, 40, 177 (1969).

    CAS  PubMed  Google Scholar 

  3. Burrows, W., Ann. Rev. Microbiol., 22, 245 (1968).

    Article  CAS  Google Scholar 

  4. Coleman, W. H., Kaur, J., Iwert, M. E., Kasai, G. J., and Burrows, W., J. Bact., 96, 1137 (1968).

    CAS  PubMed  Google Scholar 

  5. Carpenter, C. C. J., Sack, R. B., Feeley, J. C., and Steenberg, R. W., J. Clin. Invest., 47, 1210 (1968).

    Article  CAS  Google Scholar 

  6. Sack, R. B., and Carpenter, C. C. J., J. Infect. Dis., 119, 150 (1969).

    Article  CAS  Google Scholar 

  7. Mosley, W. H., and Ahmed, A., J. Bact., 100, 547 (1969).

    CAS  PubMed  Google Scholar 

  8. Felsenfeld, O., The Cholera Problem (Green, St Louis, 1967).

    Google Scholar 

  9. Mosley, W. H., McCormack, W. M., Ahmed, A., Chowdhury, A. K. M. A., and Barui, R. K., Bull. WHO, 40, 187 (1969).

    CAS  PubMed  Google Scholar 

  10. Mukerjee, S., Bull. WHO, 29, 753 (1963).

    CAS  PubMed  Google Scholar 

  11. Bhaskaran, K., J. Gen. Microbiol., 23, 47 (1960).

    Article  CAS  Google Scholar 

  12. Schwartz, D. O., and Beckwith, J. R., Genetics, 61, 372 (1969).

    Google Scholar 

  13. Fowler, A. V., and Zabin, I., J. Mol. Biol., 33, 35 (1968).

    Article  CAS  Google Scholar 

  14. Craig, J. P., Nature, 207, 614 (1965).

    Article  ADS  CAS  Google Scholar 

  15. Evans, D. J., and Richardson, S. H., J. Bact., 96, 126 (1968).

    CAS  PubMed  Google Scholar 

  16. Lewis, A. C., and Freeman, B. A., Science, 165, 808 (1969).

    Article  ADS  CAS  Google Scholar 

  17. Adelberg, E. A., Mandel, M., and Chen, G. C. C., Biochem. Biophys. Res. Commun., 18, 788 (1965).

    Article  CAS  Google Scholar 

  18. Prescott, L. M., Bull. WHO, 39, 971 (1968).

    CAS  PubMed  Google Scholar 

  19. Bhaskaran, K., Sinha, V. B., and Iyer, S. S., Curr. Sci., 36, 257 (1967).

    Google Scholar 

  20. Bhattacharya, P., Narayanaswami, A., and Mukerjee, S., J. Bact., 95, 255 (1968).

    CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

HOWARD, B. A Prototype Live Oral Cholera Vaccine. Nature 230, 97–99 (1971). https://doi.org/10.1038/230097a0

Download citation

  • Received:

  • Revised:

  • Issue Date:

  • DOI: https://doi.org/10.1038/230097a0

  • Springer Nature Limited

This article is cited by

Navigation