Skip to main content
Log in

Specific Chromosome Anomaly associated with Autonomous and Cancerous Development in Man

  • Letter
  • Published:

From Nature

View current issue Submit your manuscript

Abstract

SEVERAL studies1–4 have now shown that chromosome variation in cancer cells is non-random, and that during cancer progression at least natural selection favours certain chromosome types while others are eliminated. Similar patterns of non-random representations of chromosome types have also been reported in established cell lines5–8.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Ishihara, T., Kikuchi, Y., and Sandberg, A. A., J. Nat. Cancer Inst., 30, 1303 (1963).

    CAS  PubMed  Google Scholar 

  2. Makino, S., Sasaki, M. S., and Tonomura, A., J. Nat. Cancer Inst., 32, 741 (1964).

    Google Scholar 

  3. Van Steenis, H., Nature, 209, 819 (1966).

    Article  ADS  CAS  PubMed  Google Scholar 

  4. Levan, A., Hereditas, 55, 28 (1966).

    Article  Google Scholar 

  5. Yerganian, G., Shein, H. M., and Enders, J. F., Cytogenetics, 1, 314 (1962).

    Article  CAS  PubMed  Google Scholar 

  6. Moorhead, P. S., and Saksela, E., J. Cell Comp. Physiol., 62, 57 (1963).

    Article  CAS  PubMed  Google Scholar 

  7. German, J. L., Evans, V. J., Cortner, J. A., and Westfall, B. B., J. Nat. Cancer Inst., 32, 681 (1964).

    PubMed  Google Scholar 

  8. Hampel, K., and Levan, A., Hereditas, 51, 315 (1964).

    Article  Google Scholar 

  9. Levan, A., Hereditas, 57, 343 (1967).

    Article  CAS  PubMed  Google Scholar 

  10. Carr, D. H., Amer. J. Obst. Gynec., 104, 327 (1969).

    Article  CAS  Google Scholar 

  11. Polani, P. E., Develop. Med. Child Neurol., 8, 67 (1966).

    Article  CAS  PubMed  Google Scholar 

  12. Hecht, F., Case, M. P., Lovrian, E. W., and Higgins, J. V., Science, 161, 371 (1968).

    Article  ADS  CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

MULDAL, S., ELEJALDE, R. & HARVEY, P. Specific Chromosome Anomaly associated with Autonomous and Cancerous Development in Man. Nature 229, 48–49 (1971). https://doi.org/10.1038/229048a0

Download citation

  • Received:

  • Revised:

  • Issue Date:

  • DOI: https://doi.org/10.1038/229048a0

  • Springer Nature Limited

This article is cited by

Navigation