Skip to main content
SpringerLink
Log in

Three Dimensional Fourier Synthesis of Horse Deoxyhaemoglobin at 2.8 Å Resolution

  • Letter
  • Published:

From Nature

View current issue Submit your manuscript

An Erratum to this article was published on 14 November 1970

Abstract

THE deoxyhaemoglobin of horse forms orthorhombic crystals with the space group C2221 and four molecules in the unit cell, which lie on two-fold symmetry axes. A Fourier synthesis at 5.5 Å resolution showed the tertiary structures of the individual subunits to be closely similar to that of oxyhaemoglobin, but the quaternary structure of the tetramer to be markedly different1,2.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Perutz, M. F., Bolton, W., Diamond, R., Muirhead, H., and Watson, H. C., Nature, 203, 687 (1964).

    Article  ADS  CAS  Google Scholar 

  2. Bolton, W., Cox, J. M., and Perutz, M. F., J. Mol. Biol., 33, 283 (1968).

    Article  CAS  Google Scholar 

  3. Arndt, U. W., Crowther, R. A., and Mallett, J. F. W., J. Sci. Instrum. (J. Phys., E), 1, 509 (1968).

    ADS  Google Scholar 

  4. Matthews, B. W., Sigler, P. B., Henderson, R., and Blow, D. M., Nature, 214, 652 (1967).

    Article  ADS  CAS  Google Scholar 

  5. Richards, F. M., J. Mol. Biol., 37, 225 (1968).

    Article  CAS  Google Scholar 

  6. Muirhead, H., and Perutz, M. F., Nature, 199, 633 (1963).

    Article  ADS  CAS  Google Scholar 

  7. Perutz, M. F., Muirhead, H., Cox, J. M., and Goaman, L. C. G., Nature, 219, 131 (1968).

    Article  ADS  CAS  Google Scholar 

  8. Muirhead, H., and Greer, J., Nature, 228, 516 (1970) (this issue).

    Article  ADS  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. MRC Laboratory of Molecular Biology, Hills Road, Cambridge

    W. BOLTON & M. F. PERUTZ

Authors
  1. W. BOLTON
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. M. F. PERUTZ
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

BOLTON, W., PERUTZ, M. Three Dimensional Fourier Synthesis of Horse Deoxyhaemoglobin at 2.8 Å Resolution. Nature 228, 551–552 (1970). https://doi.org/10.1038/228551a0

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1038/228551a0

  • Springer Nature Limited

This article is cited by

Search

Navigation