Skip to main content
SpringerLink
Log in

Separation of RNA-dependent DNA Polymerase Activity from the Murine Leukaemia Virion

  • Article
  • Published:

From Nature

View current issue Submit your manuscript

Abstract

DNA polymerase activity has been separated from intact virions and is found associated with the nucleoid. Antiserum to the viral proteins inhibits this activity.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Baltimore, D., Nature, 226, 1209 (1970).

    Article  ADS  CAS  Google Scholar 

  2. Temin, H. M., and Mizutani, S., Nature, 226, 1201 (1970).

    Article  ADS  Google Scholar 

  3. Scolnick, E. M., Aaronson, S. A., and Todaro, G. J., Proc. US Nat. Acad. Sci., 67, 660 (1970).

    Article  ADS  Google Scholar 

  4. Huebner, R. J., and Todaro, G. J., Proc. US Nat. Acad. Sci., 64, 1087 (1969).

    Article  ADS  CAS  Google Scholar 

  5. Hatanaka, M., Huebner, R. J., and Gilden, R., Proc. US Nat. Acad. Sci., 67, 143 (1970).

    Article  ADS  CAS  Google Scholar 

  6. Spiegelman, S., Burny, A., Das, M., Keydar, J., Schlom, J., Trávníček, M., and Watson, K., Nature, 227, 1029 (1970).

    Article  ADS  CAS  Google Scholar 

  7. Todaro, G. J., Zeve, V., and Aaronson, S. A., In Vitro (in the press).

  8. Fink, M. A., Sibal, L. R., Wivel, N. A., Coates, C. A., and O'Connor, T. E., Virology, 37, 605 (1969).

    Article  CAS  Google Scholar 

  9. Smith, K. O., in Methods in Cancer Research, 1, 545 (1967).

    Google Scholar 

  10. Caspar, D. L. D., Dulbecco, R., Klug, A., Lwoff, A., Stoker, M. G. P., Tournier, P., and Wildy, p., Cold Spring Harbor Symp. Quant. Biol., 27, 49 (1962).

    Article  CAS  Google Scholar 

  11. Huebner, R. J., Proc. US Nat. Acad. Sci., 58, 835 (1967).

    Article  ADS  CAS  Google Scholar 

  12. Rokutanda, M., Rokutanda, H., Green, M., Fujinaga, K., Ray, R. K., and Gurgo, C., Nature, 227, 1026 (1970).

    Article  ADS  CAS  Google Scholar 

  13. McDonnell, J. P., Garapin, A., Levinson, W., Quintrell, N., Fanshier, L., and Bishop, J. M., Nature, 228, 433 (1970).

    Article  ADS  CAS  Google Scholar 

  14. Lowry, O. H., Rosebrough, N. J., Farr, A. L., and Randall, R. J., J. Biol. Chem., 193, 265 (1951).

    CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. National Cancer Institute, Bethesda, Maryland, 20014

    BRENDA I. GERWIN, GEORGE J. TODARO, VICTOR ZEVE, EDWARD M. SCOLNICK & STUART A. AARONSON

  2. Molecular Anatomy Program, US Atomic Energy Commission, Rockville, Maryland, 20014

    BRENDA I. GERWIN

Authors
  1. BRENDA I. GERWIN
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. GEORGE J. TODARO
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. VICTOR ZEVE
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. EDWARD M. SCOLNICK
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. STUART A. AARONSON
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

GERWIN, B., TODARO, G., ZEVE, V. et al. Separation of RNA-dependent DNA Polymerase Activity from the Murine Leukaemia Virion. Nature 228, 435–438 (1970). https://doi.org/10.1038/228435a0

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1038/228435a0

  • Springer Nature Limited

This article is cited by

Search

Navigation