Skip to main content
SpringerLink
Log in

Detection of Inactive Enzyme Molecules in Ageing Organisms

  • Article
  • Published:

From Nature

View current issue Submit your manuscript

Abstract

Using immunochemical techniques, evidence is obtained that older nematodes (Turbatrix aceti) contain two populations of enzyme molecules—one active and the other totally inactive.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Yanofsky, C., and Stadler, J., Proc. US Nat. Acad. Sci., 44, 245 (1958).

    Article  ADS  CAS  Google Scholar 

  2. Gershon, D., Exp. Gerontol. (in the press).

  3. Pai, S., Z. Wiss. Zool., 131, 293 (1928).

    Google Scholar 

  4. Rothstein, M., and Cook, E., Comp. Biochem. Physiol., 17, 638 (1966).

    Google Scholar 

  5. Erlanger, M., and Gershon, D., Exp. Gerontol. (in the press).

  6. Rothstein, M., and Mayoh, H., Comp. Biochem. Physiol., 16, 361 (1965).

    Article  CAS  PubMed  Google Scholar 

  7. John, P. C. L., and Syrett, P. J., Biochem. J., 105, 409 (1967).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  8. Shiio, I., Shiio, T., and McFadden, B. A., Biochim. Biophys. Acta, 96, 114 (1965).

    Article  CAS  PubMed  Google Scholar 

  9. Dixon, M., and Kornberg, H. L., Biochem. J., 72, 3P (1955).

    Google Scholar 

  10. Lowry, O. H., Rosebrough, N. J., Farr, A. L., and Randall, R. J., J. Biol. Chem., 193, 265 (1951).

    CAS  PubMed  Google Scholar 

  11. Kabat, E. A., and Mayer, M. M., Experimental Immunochemistry, second ed., chap. 2 (Thomas, Springfield, 1961).

    Google Scholar 

  12. Cinader, B., in Antibodies to Biologically Active Molecules (edit. by Cinader. B.), 85 (Pergamon, London, 1967).

    Google Scholar 

  13. Orgel, L. E., Proc. US Nat. Acad. Sci., 49, 517 (1963).

    Article  ADS  CAS  Google Scholar 

  14. Palmer, W. G., and Papaconstantinou, J., Proc. US Nat. Acad. Sci., 64, 404 (1969).

    Article  ADS  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Laboratory of Biochemistry, Department of Chemistry, Israel Institute of Technology, Haifa

    HARRIET GERSHON & DAVID GERSHON

Authors
  1. HARRIET GERSHON
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. DAVID GERSHON
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

GERSHON, H., GERSHON, D. Detection of Inactive Enzyme Molecules in Ageing Organisms. Nature 227, 1214–1217 (1970). https://doi.org/10.1038/2271214a0

Download citation

  • Received:

  • Revised:

  • Issue Date:

  • DOI: https://doi.org/10.1038/2271214a0

  • Springer Nature Limited

This article is cited by

Search

Navigation