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Experimental Transmission of Feline Fibrosarcoma to Cats and Dogs

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Abstract

An infectious C-type feline sarcoma virus (FSV), isolated from a naturally occurring fibrosarcoma of a domestic house cat, produces fibrosarcomas in kittens and puppies and induces cell transformation in feline embryo fibroblasts. Prenatal inoculation of cat and dog foetuses is particularly effective in tumour transmission. Postnatal dogs bearing FSV induced fibrosarcomas provide antisera suitable for detecting the feline C-type RNA tumour virus antigens in the complement fixation test.

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Authors and Affiliations

  1. Department of Pathology, University of Southern California School of Medicine, Los Angeles, California

    MURRAY B. GARDNER & ROBERT W. RONGEY

  2. Viral Carcinogenesis Branch, National Cancer Institute, Bethesda, Maryland

    PAUL ARNSTEIN, JOHN D. ESTES, PADMAN SARMA & ROBERT J. HUEBNER

  3. New York State Veterinary College, Cornell University, Ithaca, New York

    CHARLES G. RICKARD

Authors
  1. MURRAY B. GARDNER
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  2. ROBERT W. RONGEY
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  3. PAUL ARNSTEIN
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  4. JOHN D. ESTES
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  5. PADMAN SARMA
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  6. ROBERT J. HUEBNER
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  7. CHARLES G. RICKARD
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GARDNER, M., RONGEY, R., ARNSTEIN, P. et al. Experimental Transmission of Feline Fibrosarcoma to Cats and Dogs. Nature 226, 807–809 (1970). https://doi.org/10.1038/226807a0

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  • DOI: https://doi.org/10.1038/226807a0

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