Abstract
IT has been proposed that cell adhesion involves the participation of actomyosin-like protein located in the surface1. The theory was based mainly on the similarity between actomyosin proteins in muscle2–5 and non-muscle cells6–8, a comparison of the properties of actomyosin protein with the effects of calcium and of nucleoside phosphates9–11 on cell aggregation, and evidence indicating the presence of actomyosin-like protein at the surface of liver cells12–15. Hypothetical models have been suggested for the involvement of contractile actomyosin in inter-molecular bonding between adjacent cells16–18.
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References
Jones, B. M., Nature, 212, 362 (1966).
Weber, H. H., Ann. Rev. Biochem., 26, 667 (1959).
Perry, S. V., in Comparative Biochemistry (edit. by Florkin, M., and Mason, H. S.) 2, 245 (Academic Press, New York, 1960).
Szent-Györgyi, A. G., in Structure and Function of Muscle (edit. by Bourne, G. H.), 2, 1 (Academic Press, New York, 1960).
Huxley, H. E., and Hanson, J., in Structure and Function of Muscle (edit. by Bourne, G. H.), 1, 183 (Academic Press, New York, 1960).
Weber, H. H., The Motility of Muscle and Cells (Harvard Univ. Press, 1958).
Hoffman-Berling, H., Biochim. Biophys. Acta, 19, 453 (1956).
Bettex-Galland, M., and Lüscher, E. F., Adv. Protein Chem., 20, 1 (1965).
Gaarder, A., Jonsen, J., Laland, S., Hellem, A. J., and Owen, P. A., Nature, 192, 531 (1961).
Mitchell, J. R. A., and Sharp, A. A., Brit. J. Haematol, 10, 78 (1964).
Knight, V. A., Jones, B. M., and Jones, P. C. T., Nature, 210, 1008 (1966).
Neifakh, S. A., and Vasilets, I. M., Vopr. Med. Khimii, 10, 326 (1964).
Vasilets, I. M., Biokhimiya, 29, 983 (1964).
Neifakh, S. A., and Vasilets, I. M., Tsitologiya, 7, 347 (1965).
Vasilets, I. M., and Zubzhitskii, Yu N., Biokhimiya, 31, 453 (1966).
Jones, B. M., Sci. J., 3, 73 (1967).
Booyse, F. M., and Rafelson, M. E., Blood, 33, 100 (1969).
Jones, B. M., and Morrison, G. A., J. Cell Sci., 4, 799 (1969).
Winnick, T., and Goldwasser, R., Exp. Cell Res., 25, 428 (1961).
Gröschel-Stewart, U., and Gigli, I., Experientia, 24, 65 (1968).
Gröschel-Stewart, U., Experientia, 25, 601 (1969).
Groschel-Stewart, U., Fifth Symp. Fed. Europ. Biochem. Soc., Abstract No. 255 (1968).
Huys, J., Bull. Soc. Roy. Belge Gynec. Obst., 33, 429 (1963).
Gröschel-Stewart, U., and Turba, F., Biochem. Z., 337, 104 (1963).
Finck, H., Biochim. Biophys. Acta, 111, 208 (1966).
Kemp, R. B., Jones, B. M., Cunningham, I., and James, M. C. M., J. Cell Sci., 2, 323 (1967).
Moscona, A. A., Exp. Cell Res., 22, 155 (1961).
Jones, B. M., Nature, 205, 1280 (1965).
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JONES, B., KEMP, R. & GRÖSCHEL-STEWART, U. Inhibition of Cell Aggregation by Antibodies directed against Actomyosin. Nature 226, 261–262 (1970). https://doi.org/10.1038/226261a0
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DOI: https://doi.org/10.1038/226261a0
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