Abstract
Contrary to a previous report, messenger RNA for the tryptophan operon is degraded in the 5′—3′ direction. The following two articles describe how pulse labelling and hybridization experiments established this. In some conditions, the degradation of individual messengers starts before their synthesis is complete.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Baker, R. F., and Yanofsky, C., Nature, 219, 26 (1968).
Morse, D. E., Mosteller, R., Baker, R. F., and Yanofsky, C., Nature, 223, 40 (1969) (following article).
Yanofsky, C., and Ito, J., J. Mol. Biol., 21, 313 (1966).
Matsushiro, A., Sato, K., Ito, J., Kida, S., and Imamoto, F., J. Mol. Biol., 11, 54 (1965).
Ito, J., and Imamoto, F., Nature, 220, 441 (1968).
Vogel, H., and Bonner, D. M., J. Biol. Chem., 218, 97 (1956).
Imamoto, F., Morikawa, N., Sato, K., Mishima, S., Nishimura, T., and Matsushiro, A., J. Mol. Biol., 13, 157 (1965).
Deeb, S. S., Okamoto, K., and Hall, B. D., Virology, 31, 289 (1967).
Imamoto, F., and Ito, J., Nature, 220, 27 (1968).
Imamoto, F., Morikawa, N., and Sato, K., J. Mol. Biol., 13, 169 (1965).
Imamoto, F., and Yanofsky, C., J. Mol. Biol., 28, 1 (1967).
Nossal, N. G., and Singer, M. F., J. Biol. Chem., 243, 913 (1968).
Singer, M. F., and Leder, P., Ann. Rev. Biochem., 35, 195 (1966).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
MORIKAWA, N., IMAMOTO, F. Degradation of Tryptophan Messenger: On the Degradation of Messenger RNA for the Tryptophan Operon in Escherichia coli. Nature 223, 37–40 (1969). https://doi.org/10.1038/223037a0
Received:
Issue Date:
DOI: https://doi.org/10.1038/223037a0
- Springer Nature Limited
This article is cited by
-
Control of mRNA processing and decay in prokaryotes
Genetica (1994)
-
Control of RNase E-mediated RNA degradation by 5′-terminal base pairing in E. coil
Nature (1992)
-
Evidence for endonucleolytic cleavage at the 5′-proximal segment of the trp messenger RNA in Escherichia coli
Molecular and General Genetics MGG (1979)
-
Decay rates of Escherichia coli trp messenger RNA molecules lacking the normal 5′-terminal sequences
Molecular and General Genetics MGG (1979)
-
Synthesis and degradation of lac mRNA in E. coli depleted of 30S ribosomal subunits
Molecular and General Genetics MGG (1979)