Abstract
THE susceptibility of C3H male mice to the apparently spontaneous development of hepatomas has long been recognized1. Castration reduces the incidence of these tumours2 and a high protein diet increases it3.
Similar content being viewed by others
References
Burns, E. L., and Schrinken, J. R., Amer. J. Cancer, 39, 25 (1940).
Andervont, H. B., J. Nat. Cancer Inst., 11, 581 (1950).
Tannenbaum, A., and Silverstone, H., Cancer Res., 9, 162 (1949).
Roe, F. J. C., and Walters, M. A., Nature, 214, 299 (1967).
Gorrod, J. W., Carter, R. L., and Roe, F. J. C., J. Nat. Cancer Inst., 41, 403 (1968).
Roe, F. J. C., Carter, R. L., and Adamthwaite, S., Nature, 221, 1063 (1969).
Epstein, S. S., Andrea, J., Jaffs, H., Joshi, S., Falk, H., and Mantel, L., Nature, 215, 1388 (1967).
Pollard, M., Matsuzawa, T., and Salomon, J. C., J. Nat. Cancer Inst., 33, 93 (1964).
Pollard, M., Nature, 211, 1289 (1963).
Pollard, M., and Kajima, M., J. Nat. Cancer Inst., 39, 135 (1967).
Laqueur, G. L., and Matsumoto, H., J. Nat. Cancer Inst., 37, 217 (1966).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
GRANT, G., ROE, F. Influence of Germ-free Status on Hepatoma Induction by 7,12-Dimethylbenz(a)anthracene in C3H Mice. Nature 222, 1282–1283 (1969). https://doi.org/10.1038/2221282a0
Received:
Issue Date:
DOI: https://doi.org/10.1038/2221282a0
- Springer Nature Limited