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Carcinogenic Action of Elaiomycin in Rats

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Abstract

SEVERAL natural products of plant or microbial origin have been discovered in the past 20 yr that have proved carcinogenic in experimental animals1. These products include certain pyrrolizidine alkaloids, luteoskyrin, aflatoxins, cycasin and streptozotocin2. The last two compounds are of particular interest in view of their structural relationship to the synthetic, highly carcinogenic alkyl-nitroso-compounds3.

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References

  1. Schoental, R., Bull. Wld Hlth Org., 29, 823 (1963).

    CAS  Google Scholar 

  2. Arison, R. N., and Fendale, E. L., Nature, 214, 1254 (1967).

    Article  ADS  CAS  Google Scholar 

  3. Magee, P. N., and Barnes, J. M., Adv. Cancer Res., 10, 163 (1967).

    Article  CAS  Google Scholar 

  4. Ehrlich, J., Anderson, L. E., Coffey, G. L., Feldman, W. H., Fisher, M. W., Hillegas, A. B., Karlson, A. G., Kundsen, M. P., Weston, J. K., Youmans, A. S., and Youmans, G. P., Antibiotics Chemotherap., 4, 338 (1954).

    CAS  Google Scholar 

  5. Haskell, T. H., Ryder, A., and Bartz, Q. R., Antibiotics Chemother., 4, 141 (1954).

    CAS  Google Scholar 

  6. Stevens, C. L., Gillis, B. T., French, J. C., and Haskell, T. H., J. Amer. Chem. Soc., 80, 6088 (1958).

    Article  CAS  Google Scholar 

  7. Schoental, R., and Bensted, J. P. M., Brit. J. Cancer, 22, 316 (1968).

    Article  CAS  Google Scholar 

  8. Schoental, R., in Epidemiological, Experimental and Clinical Studies on Gastric Cancer, Gann Monog. 3, 61 (Maruzen Co., Tokyo, 1968).

    Google Scholar 

  9. Herr, R. R., Jahnke, H. K., and Argoudelis, A. D., J. Amer. Chem. Soc., 89, 4808 (1967).

    Article  CAS  Google Scholar 

  10. Ohkuma, K., Nakamura, G., and Yamashita, S., J. Antibiot. (Japan), Ser. A, 10, 224 (1957).

    CAS  Google Scholar 

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SCHOENTAL, R. Carcinogenic Action of Elaiomycin in Rats. Nature 221, 765–766 (1969). https://doi.org/10.1038/221765a0

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  • DOI: https://doi.org/10.1038/221765a0

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