Abstract
The secondary structure of the haemoglobin chains is similar to that of myoglobin, but some of the helical segments are more irregular and some parts of the non-helical segments have different conformations. The structure of the contacts between unlike subunits suggests that the tetramer, rather than the αβ dimer, is the functional unit of haemoglobin.
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PERUTZ, M., MUIRHEAD, H., COX, J. et al. Three-dimensional Fourier Synthesis of Horse Oxyhaemoglobin at 2.8 Å Resolution: The Atomic Model. Nature 219, 131–139 (1968). https://doi.org/10.1038/219131a0
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DOI: https://doi.org/10.1038/219131a0
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