Skip to main content

Advertisement

SpringerLink
Log in

Aureolic Acid Group of Anti-tumour Antibiotics

  • Letter
  • Published:

From Nature

View current issue Submit your manuscript

Abstract

SINCE 1953 several antibiotics of similar biological and physico-chemical properties have been described. These are aureolic acid1, aburamycin2, LA-7017 (ref. 3), M5-18903 (ref. 4), chromomycin5, antibiotic 2410 (ref. 6), NSC A-649 (ref. 7), olivomycin8, mithramycin9 and antibiotics 232, 3014, 7193, 11296 (ref. 10) and SK-229 (ref. 11). Two members of this group, olivomycin and chromomycin, were subjected to extensive chemical research which resulted in the isolation and structural elucidation of their components, olivomycins A, B, C, D (ref. 12) and chromomycins A2, A3, A4 (ref. 13). The other members of the group, however, have been only scantily investigated.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Grundy, W. E., Goldstein, A. W., Rickher, C. J., Hanes, M. E., Warren, H. B., and Sylvester, J. C., Antibiot. Chemother., 3, 1215 (1953); Philip, J. E., and Schenck, J. R., ibid., 1218.

    CAS  Google Scholar 

  2. Nishimura, H., Kimura, T., Tawara, K., Sasaki, K., Nakajima, K., Shimaoka, N., Okamoto, S., Shimohira, M., and Isono, J., J. Antibiot. (Tokyo). Ser. A 10, 205 (1957).

    CAS  PubMed  Google Scholar 

  3. Sensi, P., Greco, A. M., and Pagani, H., Antibiot. Chemother., 8, 241 (1958).

    CAS  Google Scholar 

  4. Gale, R. M., Hoehn, M. M., and McCormick, M. H., Antibiot. Ann., 489 (1958).

  5. Shibata, M., Tanabe, K., Hamada, Y., Nakazawa, K., Miyake, A., Hitomi, M., Miyamoto, M., and Mizuno, K., J. Antibiot. (Tokyo), Ser. B 13, 1 (1960).

    CAS  Google Scholar 

  6. Bringi, N. V., Bhatt, V. V., and Thirumalachar, M. J., Hind. Antibiot. Bull., 2, 120 (1960).

    Google Scholar 

  7. Schmitz, H., Heinemann, B., Lein, J., and Hooper, I. R., Antibiot. Chemother., 10, 740 (1960).

    CAS  Google Scholar 

  8. Gauze, G. F., Ukholina, R. S., and Sveshnikova, M. A., Antibiotiki, 7 (3), 34 (1962); Brazhnikova, M. G., Kruglyak, E. B., Kovsharova, I. N., Konstantinova, N. V., and Proshlyakova, V. V., ibid., 39.

    CAS  Google Scholar 

  9. Rao, K. V., Cullen, W. P., and Sobin, B. A., Antibiot. Chemother., 12, 182 (1962).

    CAS  Google Scholar 

  10. Ukholina, R. S., Kruglyak, E. B., Borisova, V. N., Kovsharova, I. N., and Proshlyakova, V. V., Mikrobiologia, 34, 147 (1965).

    CAS  Google Scholar 

  11. Yoshida, T., Matsuura, S., Sunagawa, N., Suetomi, S., Kimura, Y., and Katagiri, K., Ann. Rep. Shionogi Res. Lab., 15, 212 (1965).

    Google Scholar 

  12. Berlin, Yu. A., Esipov, S. E., Kolosov, M. N., and Shemyakin, M. M., Tetrahedron Lett., 1431, 1643 (1966); Bakhaeva, G. P., Berlin, Yu. A., Chuprunova, O. A., Kolosov, M. N., Peck, G. Yu., Piotrovich, L. A., Shemyakin, M. M., and Vasina, I. V., Chem. Commun., 10 (1967).

  13. Miyamoto, M., Kawamatsu, Y., Kawashima, K., Shinohara, M., Tanaka, K., Tatsuoka, S., and Nakanishi, K., Tetrahedron, 23, 421 (1967).

    Article  CAS  Google Scholar 

  14. Brazhnikova, M. G., Kruglyak, E. B., Mezentsev, A. S., and Fedorova, G. B., Antibiotiki, 9, 552 (1964); Berlin, Yu. A., Esipov, S. E., Kolosov, M. N., Shemyakin, M. M., and Brazhnikova, M. G., Tetrahedron Lett., 1323 (1964).

    CAS  PubMed  Google Scholar 

  15. Miyamoto, M., Morita, K., Kawamatsu, Y., Noguchi, S., Marumoto, R., Tanaka, K., Tatsuoka, S., Nakanishi, K., Nakadaira, Y., and Bhacca, N. S., Tetrahedron Lett., 2355 (1964).

  16. Brazhnikova, M. G., Kruglyak, E. B., and Mezentsev, A. S., Antimicrob. Agents Chemother., 119 (1966).

  17. Kruglyak, E. B., Borisova, V. N., and Brazhnikova, M. G., Antibiotiki, 8, 1064 (1963).

    CAS  Google Scholar 

  18. Gauze, G. F., Maximova, T. S., Ukholina, R. S., Brazhnikova, M. G., and Kruglyak, E. B., Antibiotiki, 12 (12) (1967).

Download references

Author information

Authors and Affiliations

  1. Institute for Chemistry of Natural Products, USSR Academy of Sciences, Moscow

    Yu. A. BERLIN, O. A. KISELEVA, M. N. KOLOSOV, M. M. SHEMYAKIN, V. S. SOIFER, I. V. VASINA & I. V. YARTSEVA

  2. All-Union Institute of Antibiotics Research, Moscow

    V. D. KUZNETSOV

Authors
  1. Yu. A. BERLIN
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. O. A. KISELEVA
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. M. N. KOLOSOV
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. M. M. SHEMYAKIN
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. V. S. SOIFER
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. I. V. VASINA
    View author publications

    You can also search for this author in PubMed Google Scholar

  7. I. V. YARTSEVA
    View author publications

    You can also search for this author in PubMed Google Scholar

  8. V. D. KUZNETSOV
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

BERLIN, Y., KISELEVA, O., KOLOSOV, M. et al. Aureolic Acid Group of Anti-tumour Antibiotics. Nature 218, 193–194 (1968). https://doi.org/10.1038/218193a0

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/218193a0

  • Springer Nature Limited

This article is cited by

Search

Navigation