Abstract
ACCORDING to many authors1–4, the secondary immunological response should consist of responses of cells endowed with immunological memory (Y cells in the scheme of Sercarz and Coons3) acquired during contact with antigen administered in the previous immunization, and of cells which had come into contact with the antigen for the first time (X and Z cells according to Sercarz and Coons).
Similar content being viewed by others
References
Nossal, G. J. V., Austin, C. M., and Ada, G. L., Immunology, 9, 333 (1965).
Sercarz, E. E., and Byers, V. S., J. Immunol., 98, 836 (1967).
Sercarz, E. E., and Coons, A. H., Mechanisms of Immunological Tolerance (Czechoslovak. Acad. Sci., Prague, 1962).
Šterzl, J., Nature, 209, 416 (1966).
Šterzl, J., and Mandel, L., Folia Microbiol., 9, 173 (1964).
Jerne, N. K., Nordin, A. A., and Henry, C., in Amos, B., and Koprowski, H., Cell-Bound Antibodies, 109 (The Wistar Institute Press, Philadelphia, 1963).
Adler, F. L., J. Immunol., 95, 26 (1965).
Halasa, J., Folia Microbiol. (in the press).
Moller, G., and Wigzell, H., J. Exp. Med., 121, 969 (1965).
Rowley, D. A., and Fitch, F. W., J. Exp. Med., 120, 987 (1964).
Greenbury, C. L., and Moore, D. H., Immunology, 6, 421 (1963).
Schwartz, R., Stock, J., and Dameshek, W., Proc. Soc. Exp. Biol., NY, 99, 164 (1958).
Šterzl, J., Zurnal Higieny, Epidemiologii, Mikrobiologii i Immunologii, 7, 323 (1963).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
HALASA, J. Role of X, Y and Z Cells in Secondary Immunological Response. Nature 217, 859–860 (1968). https://doi.org/10.1038/217859a0
Received:
Revised:
Issue Date:
DOI: https://doi.org/10.1038/217859a0
- Springer Nature Limited