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Mutagenic Capacity of Adenoviruses for Mammalian Cells

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Abstract

Adenoviruses are mutagenic for mammalian cells. Viral replication, which results in a cytocidal effect, seems to be independent of a mutagenic effect caused by adenoviruses which initiate, but do not complete, a full replication cycle.

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References

  1. Hampar, B. H., and Ellison, S. A., Proc. US Nat. Acad. Sci., 49, 474 (1963). Nichols, W. W., Hereditas, 50, 53 (1963). Stich, H. F., Van Hoosier, G. L., and Trentin, J. J., Exper. Cell Res., 34, 400 (1964).

    Article  ADS  CAS  Google Scholar 

  2. Huebner, R. J., Rowe, W. P., Turner, H. C., and Lane, W. T., Proc. US Nat. Acad. Sci., 50, 379 (1963).

    Article  ADS  CAS  Google Scholar 

  3. Berman, L. D., and Rowe, W. P., J. Exp. Med., 121, 955 (1965).

    Article  CAS  Google Scholar 

  4. MacKinnon, E. A., Kalnins, V. I., Stich, H. F., and Yohn, D. S., Cancer Res., 26, 612 (1966).

    CAS  PubMed  Google Scholar 

  5. Kalnins, V. I., Stich, H. F., Gregory, C., and Yohn, D. S., Cancer Res. (inthe press).

  6. Huebner, R. J., in Prospectives in Virology V, 147 (1967); and Fujinaga, K., and Green, M., Proc. US Nat. Acad. Sci., 57, 866 (1967).

    Google Scholar 

  7. Cooper, J. E. K., Stich, H. F., and Yohn, D. S., Virology (in the press).

  8. Pope, J. H., and Rowe, W. P., J. Exper. Med., 120, 577 (1964).

    Article  CAS  Google Scholar 

  9. Gilead, Z., and Ginsberg, H. S., J. Bacteriol., 92, 1853 (1966).

    CAS  PubMed  PubMed Central  Google Scholar 

  10. Atchison, R. W., Casto, B. C., and Hammon, W. M. D., Science, 149, 754 (1965).

    Article  ADS  CAS  Google Scholar 

  11. Melnick, J. L., Mayor, H. D., Smith, K. O., and Rapp, F., J. Bacteriol., 90, 271 (1965).

    CAS  PubMed  PubMed Central  Google Scholar 

  12. Stich, H. F., and Yohn, D. S., J. Nat. Cancer Inst., 35, 603 (1965).

    CAS  PubMed  Google Scholar 

  13. Stoltz, D. B., Stich, H. F., and Yohn, D. S., Cancer Res., 27, 587 (1967).

    CAS  PubMed  Google Scholar 

  14. Habel, K., Cancer Res., 26, 2018 (1966).

    CAS  PubMed  Google Scholar 

  15. Fujinaga, K., and Green, M., Proc. US Nat. Acad. Sci., 55, 1567 (1966).

    Article  ADS  CAS  Google Scholar 

  16. Hauschka, T., Cancer Res., 21, 957 (1961).

    CAS  PubMed  Google Scholar 

  17. Hsu, T. C., Rev. Cytol., 12, 69 (1961).

    Article  CAS  Google Scholar 

  18. Stich, H. F., Proc. Can. Cancer Cong., 5, 99 (1963).

    CAS  Google Scholar 

  19. Stich, H. F., Exper. Cell Res., 9, 272 (1963).

    Article  Google Scholar 

  20. Defendi, V., and Jensen, F., Science, 157, 703 (1967).

    Article  ADS  CAS  Google Scholar 

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Authors and Affiliations

  1. Department of Biology, McMaster University, Hamilton, Canada

    H. F. STICH & D. S. YOHN

  2. Viral Oncology Section, Roswell Park Memorial Institute, Buffalo, USA

    H. F. STICH & D. S. YOHN

Authors
  1. H. F. STICH
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  2. D. S. YOHN
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STICH, H., YOHN, D. Mutagenic Capacity of Adenoviruses for Mammalian Cells. Nature 216, 1292–1294 (1967). https://doi.org/10.1038/2161292a0

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