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Formation of Prothrombin Converting Activity

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Abstract

After measurement of the conversion of prothrombin to thrombin in a purified system, a model has been constructed for the kinetics of the formation of prothrombin converting activity. In the model phospholipid provides a surface on to which coagulant factors bind.

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Authors and Affiliations

  1. Nuffield Department of Clinical Biochemistry, Radcliffe Infirmary, Oxford

    H. C. HEMKER, M. P. ESNOUF, P. W. HEMKER, A. C. W. SWART & R. G. MACFARLANE

  2. Laboratory of Coagulation Biochemistry, Hematology Section, Department of Internal Medicine, University Hospital, Leyden

    H. C. HEMKER, M. P. ESNOUF, P. W. HEMKER, A. C. W. SWART & R. G. MACFARLANE

Authors
  1. H. C. HEMKER
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  2. M. P. ESNOUF
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  3. P. W. HEMKER
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  4. A. C. W. SWART
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  5. R. G. MACFARLANE
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HEMKER, H., ESNOUF, M., HEMKER, P. et al. Formation of Prothrombin Converting Activity. Nature 215, 248–251 (1967). https://doi.org/10.1038/215248a0

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  • DOI: https://doi.org/10.1038/215248a0

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